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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Alpha synuclein control peptide (116-131)/PE-1606-100/100 µg
产品编号:PE-1606-100
市  场 价:¥1340.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$67.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Alpha synuclein control peptide (116-131)/PE-1606-100/100 µg
商品介绍
DescriptionAlphasynucleinisanabundant140aminoacidneuronalprotein,expressedprimarilyatpresynapticterminalsinthecentralnervoussystem.Alphasynucleinhasbeenassociatedwithseveralneurodegenerativediseases.Apointmutationinthegenecodingforthealpha-synucleinproteinwasthefirstdiscoverylinkingthisproteintoararefamilialformofParkinson"sdisease(PD).Subsequently,othermutationsinthealpha-synucleingenehavebeenidentifiedinfamilialPD.TheaggregatedproteinaceousinclusionscalledLewybodiesfoundinPDandcorticalLewybodydementia(LBD)werediscoveredtobepredominantlyalpha-synuclein.Aberrantaggregationofalpha-synucleinhasbeendetectedinanincreasingnumberofneurodegenerativediseases,collectivelyknownassynucleopathies.Alpha-synucleinexistsphysiologicallyinbothsolubleandmembrane-boundstates,inunstructuredandalpha-helicalconformations,respectively.Thephysiologicalfunctionofalpha-synucleinappearstorequireitstranslocationbetweenthesesubcellularcompartmentsandinterconversionbetweenthe2conformations.Abnormalprocessingofalpha-synucleinispredictedtoleadtopathologicalchangesinitsbindingpropertiesandfunction.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenAsyntheticpeptide(CMPVDPDNEAYEMPSEE)ofhumanalphasynucleinprotein(aa:116-131).
OtherNamesNon-AbetacomponentofADamyloid;Non-A4componentofamyloidprecursor;NACP
AccessionP37840SYUA_HUMAN;
PurityCrude
ApplicationsControlPeptide.Thispeptidemaybeusedtoblockthebindingactivityofantibodiestoalphasynuclein(seeBiosensisantibodiesS-024-100andS-075-50).
BlastURLClickhere
FormLyophilized
ReconstitutionThispeptideissolubleinPBSandwater.
StorageAfterreconstitutionkeepat-20ºC.Avoidrepetitivefreeze/thawcycles.
ExpiryDate24monthsafterpurchase
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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