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℡ 4000-520-616
℡ 4000-520-616
Biosensis/Saporin/PE-001-100/100 µg
产品编号:PE-001-100
市  场 价:¥2540.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$127.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Saporin/PE-001-100/100 µg
商品介绍
DescriptionSaporinisaribosome-inactivatingprotein(RIP)oftypeI.ThismonomericRNAN-glycosidasepurifiedfromseedsoftheplantSaponariaofficinalisalsoknownasSoapwort,iscapableofspecificdepurinationofeukaryoticribosomesthusarrestingproteinsynthesis.NoligandhasbeenidentifiedinsaporinhenceitsinABIlitytotransversethecellmembrane.Duetoitstoxicityandstabilityofthestructure,saporinhasprovenextremelyusefulforconstructionofimmunotoxins.
BatchNo.Seeproductlabel
Unitsize100µg
OtherNamesSaponariaofficinalis;Commonsoapwort;ribosomeinactivatingproteinsaporin-6;SAP-6;SO-6;rRNAN-glycosidase
AccessionRIP6_SAPOF
ProducedinPurifiedfromseedsoftheplantSaponariaofficinalis.
MolecularWeight29.5kDa
HandlingOnlyqualifiedpersonnelshouldhandlethisproduct.Extremeprecautionmustbeemployedwhenhandlingthetoxin.Wearlabcoat,glovesandsafetyglasses.Thetoxinmustnotcomeintocontactwithopenwounds.Practicegoodlaboratorytechniquetoavoidauto-exposure/auto-injection!Washthoroughlyanypartofthebodyexposedtothetoxin.Contaminatedmaterialsshouldbeexposedto300mMNaOHorautoclaved.
Purity95%bySDS-PAGEandWesternBlot.
Biol.activityUponintroductionintothecells,saporinwillarresttheproteinsynthesisbydamagingtheribosmes.
FormLyophilised
ReconstitutionSaporinmaybereconstitutedinthebufferofchoiceforexamplePBS.
StorageAliquotandkeepat-20ºCforlong-termstorage.Forshorttermkeepat4ºC.Avoidrepetitivefreeze/thawcycles.
ReferencesStirpe,F.etal(1983)BiochemJ216,617-625
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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