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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Mouse monoclonal antibody to GABARAP L2 (16-26), [Clone BS392]: IgG/M-1728-100/100 µg
产品编号:M-1728-100
市  场 价:¥5940.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$297.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Mouse monoclonal antibody to GABARAP L2 (16-26), [Clone BS392]: IgG/M-1728-100/100 µg
商品介绍
Description
Ubiquitin-likemodifierinvolvedinintra-Golgitraffic.Modulatesintra-GolgitransportthroughcouplingbetweenNSFactivityandSNAREsactivation.ItfirststimulatestheATPaseactivityofNSFwhichinturnstimulatestheassociationwithGOSR1(Bysimilarity).Involvedinautophagy.PlaysaroleinmitophagywhichcontributestoregulatemitochondrialquantityandqualitybyeliminatingthemitochondriatoabasalleveltofulfillcellularenergyrequirementsandpreventingexcessROSproduction.WhereasLC3sareinvolvedinelongationofthephagophoremembrane,theGABARAP/GATE-16subfamilyisessentialforalaterstageinautophagosomematuration.SUBUNIT:Monomer.SUBCELLULARLOCATION:Golgiapparatus.TISSUESPECIFICITY:Ubiquitous.Expressedathighlevelsinthebrain,heart,prostate,ovary,spleenandskeletalmuscle.Expressedatverylowlevelsinlung,thymusandsmallintestine.SIMILARITY:BelongstotheMAP1LC3family.ESTIMATEDMOLECULARWEIGHT:13.667kDa
BatchNo.Seeproductlabel.
Unitsize100µg
AntigenAsyntheticpeptide(C-VESAKIRAKYP,aa:16-26)ofhumanGABARAPL2proteinhasbeenusedastheimmunogen.Thesequenceishomologouswithmouse,ratandbovineformofGABARAPL2.
CloneBS392
OtherNamesGamma-aminobutyricacidreceptor-associatedprotein-like2;GABA(A)receptor-associatedprotein-like2;Gangliosideexpressionfactor2;GEF-2;Generalproteintransportfactorp16;MAP1lightchain3-relatedprotein;GABARAPL2;FLC3A;GEF2
AccessionGBRL2_HUMAN
GBRL2_MOUSE
GBRL2_RAT
ProducedinMouse
MolecularWeight14kDa
PurityProteinGpurifiedmouseIgG
ApplicationsFlowCytometry(2µg/10^6cells).Otherapplicationsnotyettested.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityHuman
Cross-reactivityNotyettested.Antibodyisexpectedtodetectmouse,ratandbovineGABARAPL2proteindueto100%aminoacidsequencehomology.
FormLyophilisedfromasolutioncontainingPBSbufferpH7.4with3%trehalose,withoutpreservatives.
AppearanceWhitepowder
ReconstitutionSpinvialbrieflybeforeopening.Reconstitutein100µLofsterilewater.Centrifugetoremoveanyinsolublematerial.Finalbuffercontainsnopreservatives.
StorageAfterreconstitutiondivideintoaliquotsandstoreat-20ºCforahigherstABIlity.Antibodycontainsnopreservatives.Storeat4ºCwithanappropriateantibacterialagent.Usesterilemethods.HighestpurityGlycerol(1:1)maybeaddedforanadditionalstabilitywhenstoredatrefrigeratedorfreezingtemperatures.Avoidrepetitivefreeze/thawcycles.
ExpiryDate12monthsafterpurchaseifunopened.
References1.OkazakiN.etal.BrainRes.Mol.BrainRes.85:1-12(2000)
2.XinY.etal.Genomics74:408-413(2001)
3.TheMGCProjectTeam.GenomeRes.14:2121-2127(2004)
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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