Biosensis/Mouse monoclonal antibody to human POMC [3E11]: IgG/M-858-100/100 µg,Biosensis,,Biosensis,Biosensis inc,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Biosensis/Mouse monoclonal antibody to human POMC [3E11]: IgG/M-858-100/100 µg

产品编号：M-858-100

市场价：¥6540.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$327.00

品牌： Biosensis

公司：Biosensis

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商品介绍

Description	The POMC gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.
Batch No.	See product label
Unit size	100 µg
Antigen	Partial recombinant human POMC (205-267) with a GST tag.
Clone	[3E11]
Other Names	Corticotropin-lipotropin; Pro-oiomelanocortin; POMC
Accession	COLI_HUMAN
Produced in	Mouse
Purity	Protein G purified immunoglobulin
Applications	This antibody is recommended for WB and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Specificity	Specificity has been confirmed by WB and direct ELISA against the antigen.
Cross-reactivity	Human. Other species have not been tested.
Blast it	To see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence that you are interested in and copy and paste it HERE and blast/format it.
Form	Lyophilised from PBS pH 7.2
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	After reconstitution keep aliquots at -20ºC for higher stability or at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
Expiry Date	12 months after purchase

品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发，特别是神经营养因子和神经营养因子受体。 近30年来，Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子，我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症（AD）、帕金森氏症（PD）和肌萎缩侧索硬化（ALS）疾病，以及自噬和代谢应激障碍，包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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