Description | TISSUESPECIFICITY:Ubiquitouslyexpressed.Expressedindorsalrootganglia,trigeminalganglia,spinalchord(Lissauer"stract,dorsalhornanddorsalcolumns)(atproteinlevel).PTM:N-glycosylated.PTM:PhosphorylatedbyPKA.SIMILARITY:Belongstothetransientreceptorfamily.TrpVsubfamily.SIMILARITY:Contains3ANKrepeats. |
BatchNo. | Seeproductlabel |
Unitsize | 100µl |
Antigen | Asyntheticpeptide(C-KNSASEEDHLPLQVLQSP)ofratVRL-1protein(aa:744-761)conjugatedtoKLHhasbeenusedastheimmunogen. |
OtherNames | osm-9-likeTRPchannel2;OTRPC2 |
Accession | VRl_RAT |
Producedin | Rabbit |
Purity | Wholeserum |
Applications | IHC,Immunofluorescence,Westernblot.Recommendedtobeusedatadilutionof1:1000to1:2000forimmunohistochemistryandWesternblot,forImmunofluorescenceatadilutionof1:50to1:200infree-floatingsectionsorparaffinembeddedsections.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | Immunohistochemicalanalysisinratdorsalrootgangliaandspinalcordindicatesahighlevelofspecificityforthisantiserum.SpecificitywasalsoshownbyWesternblot. |
Cross-reactivity | ThisantibodyisknowntoreactwithratandhumanVRL-1. |
Blastit | Ifyouwouldliketousethisproductinanotherspeciesotherthanthosespecifiedhere,ortoseethesharedIDbetweentheimmunogenusedhereindifferentspeciesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis. |
Form | Lyophilised |
Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Afterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent. |
ExpiryDate | 12monthsafterpurchase |
References | 1.Caterina,etal.,Nature398,436-41(Apr1,1999). 2.Jahnel,etal.,EurJBiochem270,4264-71(Nov,2003). 3.Montell,etal.,MolCell9,229-31(Feb,2002). |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。