| Description | TISSUESPECIFICITY:Ubiquitouslyexpressed.Expressedindorsalrootganglia,trigeminalganglia,spinalchord(Lissauer"stract,dorsalhornanddorsalcolumns)(atproteinlevel).PTM:N-glycosylated.PTM:PhosphorylatedbyPKA.SIMILARITY:Belongstothetransientreceptorfamily.TrpVsubfamily.SIMILARITY:Contains3ANKrepeats. |
| BatchNo. | Seeproductlabel |
| Unitsize | 50µg |
| Antigen | Asyntheticpeptide(C-KNSASEEDHLPLQVLQSP)aspartofratVRL-1protein(aa:744-761)conjugatedtoKLHhasbeenusedastheimmunogen. |
| OtherNames | osm-9-likeTRPchannel2;OTRPC2 |
| Accession | VRL_RAT |
| Producedin | Rabbit |
| Purity | AffinityPurified. |
| Applications | IHC,Immunofluorescence,WesternblotandImmunoblot.Recommendedtobeusedataconcentrationof0.5-1µgfortheseapplications.Thisantiserumworkssuperblyforimmunohistochemistryonfree-floatingorparaffinembeddedsections.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
| Specificity | Immunohistochemicalanalysisinratdorsalrootgangliaandspinalcordindicatesahighlevelofspecificityforthisantiserum.SpecificitywasalsoshownbyWesternblot. |
| Cross-reactivity | ThisantibodyisknowntoreactwithratandhumanVRL-1. |
| Blastit | Ifyouwouldliketousethisproductinanotherspeciesotherthanthosespecifiedhere,ortoseethesharedIDbetweentheimmunogenusedhereindifferentspeciesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis. |
| Form | LyophilisedfromPBS,pH7.4,containing0.02%sodiumazideaspreservative. |
| Reconstitution | Reconstitutein50µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
| Storage | Afterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent. |
| ExpiryDate | 12monthsafterpurchase |
| References | 1.Caterina,etal.,Nature398,436-41(Apr1,1999). 2.Jahnel,etal.,EurJBiochem270,4264-71(Nov,2003). 3.Montell,etal.,MolCell9,229-31(Feb,2002). |
| MSDS |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。



