商品介绍
| Description | ResponsesevokedbylowpHandheat,andcapsaicincanbeantagonizedbycapsazepine.SIMILARITY:Belongstothetransientreceptorfamily.TrpVsubfamily.SIMILARITY:Contains3ANKrepeats. |
| BatchNo. | Seeproductlabel |
| Unitsize | 100µl |
| Antigen | Asyntheticpeptide(PSESTSHRWRGPA)ofhumancapsaicinreceptorprotein(aa:608-621)conjugatedtoKLHhasbeenusedastheantigen. |
| OtherNames | TransientreceptorpotentialcationchannelsubfamilyVmember1;TrpV1;Capsaicinreceptor;Osm-9-likeTRPchannel1;OTRPC1;Vanilloidreceptor1;TRPV1;VR1;VR-1; |
| Accession | capsaicin_HUMAN |
| Producedin | Rabbit |
| Purity | Wholeserum |
| Applications | IHC.Useat1:1000to1:2000dilution.Thisantibodyhasnotbeentestedinotherapplications.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
| Specificity | SpecificitywasconfirmedbyIHCusingfrozensectionsofratdorsalrootganglia(DRG)andspinalcord.Duetosequencehomology,similarstainingispredictedinhumanDRGandspinalcord. |
| Cross-reactivity | Human,rat.Otherspecieshavenotyetbeentested. |
| Blastit | Ifyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechosecarefully,asthesequenceyouchosemaybeaprecursorratherthanthematureproteinforexample. |
| Form | Lyophilised |
| Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
| Storage | Afterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforanadditionalstability.Avoidrepetitivefreeze/thawcycles. |
| ExpiryDate | 12monthsafterpurchase |
| SpecificReferences | 1.JabinFagelskiöldAetal(2012)Insulin-secretingINS-1EcellsexpressfunctionalTRPV1channels.Islets.2012Jan1;4(1). |
| References | 1.Caterinaetal.Nature398:436(1999). 2.Tominagaetal.Neuron.21:531-543(1998). 3.Nagy,I.etal.EurJPharmacol500:351-369(2004). |
品牌介绍
Biosensis专注于神经科学领域的抗体和试剂的开发，特别是神经营养因子和神经营养因子受体。 近30年来，Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子，我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症（AD）、帕金森氏症（PD）和肌萎缩侧索硬化（ALS）疾病，以及自噬和代谢应激障碍，包括肥胖、代谢综合征的研究、神经免疫学和炎症。
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