Description | TISSUESPECIFICITY:Predominantlyexpressedintrigeminalanddorsalrootsensoryganglia.Isoform1andisoform3arealsoexpressedinbrainandperipheralbloodmononuclearcells. |
BatchNo. | Seeproductlabel |
Unitsize | 100µl |
Antigen | Asyntheticpeptide(YFSHLKEYVAS)ofhumancapsaicinreceptorprotein(aa:531-541)conjugatedtoKLHhasbeenusedastheimmunogen. |
OtherNames | TransientreceptorpotentialcationchannelsubfamilyVmember1;TrpV1;Capsaicinreceptor;Osm-9-likeTRPchannel1;OTRPC1;Vanilloidreceptor1;TRPV1;VR1;VR-1; |
Accession | Capsaicin_HUMAN |
Producedin | Rabbit |
Purity | Wholeserum |
Applications | IHC.Useat1:1000to1:2000dilution.Thisantibodyhasnotbeentestedinotherapplications.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | ImmunohistochemicalanalysisofratDRGindicatesasuperbdegreeofspecificityforthisserum. |
Cross-reactivity | ThisantibodyisknowntoreactwithratCapsaicinandduetosequencehomologyisexpectedtoreactwithmouseCapsaicin.Otherspecieshavenotyetbeentested. |
Blastit | Ifyouwouldliketousethisproductinanotherspeciesotherthanthosespecifiedhere,ortoseethesharedIDbetweentheimmunogenusedhereindifferentspeciesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis. |
Form | Lyophilised |
Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Afterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent. |
ExpiryDate | 12monthsafterpurchase |
SpecificReferences | 1.RehmanRetal(2013)TRPV1inhibitionattenuatesIL-13mediatedasthmafeaturesinmicebyreducingairwayepithelialinjury.IntImmunopharmacol.2013Mar;15(3):597-605. |
References | 1.Caterinaetal.Nature398:436(1999). 2.Tominagaetal.Neuron.21:531-543(1998). 3.Nagy,I.etal.EurJPharmacol500:351-369(2004). |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。