Description | Thisproductisnolongeravailable.Pleaseseebelowforourrecommendedalternativeproducts.
Replacedby | R-1607-100 | BatchNo. | Seeproductlabel | Unitsize | 100µg | Antigen | Asyntheticpeptide(HELQPLAIVDQRPSSRA)correspondingtotheaminoacids351-367fromtheC-terminusofhumanConnexin-43. | OtherNames | Cx43;gapjunctionalpha-1protein;GJA1;GJAL;Gapjunction43kDaheartprotein; | Accession | P17302CXA1_HUMAN;P23242CXA1_MOUSE;P08050CXA1_RAT | Producedin | Rabbit | Purity | Affinitypurifiedonantigencolumn | Applications | Immunohistochemistry(IHC)andWesternBlotting(WB).Aconcentrationof2.0µg/mlisrecommendedforWB.ThepredictedlengthofhumanConnexin-43is382residuesandMWof43kDa.Aconcentrationof1.0-2.0µg/mlisrecommendedtodetectConnexin-43informalinfixedandparaffinembeddedtissues.Antigenretrievalisrequired.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. | Specificity | ThespecificityofthisantibodyhasbeenconfirmedbyWBandIHCagainsttheantigen. | Cross-reactivity | Human;mouse;rat;rabbit; | Blastit | Ifyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechosecarefully,asthesequenceyouchosemaybeaprecursorratherthanthematureproteinforexample. | Form | Liquid(0.5ml).50%glycerol,0.9mgNaCland0.2mgNa2HPO4 | Reconstitution | TheliquidformulationshouldbedilutedinPBS(pH7.4). | Storage | Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles. | ExpiryDate | 12monthsafterpurchase | 品牌介绍
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。
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