Description | MANFisatrophicfactorformidbraindopamineneuronsinvivo.Itpreventsthe6-OHDA-induceddegenerationofdopamineneuronsinrodentmodelsofParkinsonsdisease(Lindholmetal.,2008,Voutilainenetal.,2009).WhenadmiNISTeredafter6-OHDA-lesioningitrestoresthedopaminergicfunctionandpreventsdegenerationofdopamineneuronsinsubstantianigraparscompacta. |
BatchNo. | Seeproductlabel |
Unitsize | 100ug |
Antigen | RecombinanthumanMANFproteinproducedusingCHO-basedcellline.Immunogenispurifiedfromcellculturesupernatant. |
AntibodyType | Monoclonal |
Isotype | IgG1 |
OtherNames | ARMET,ARP |
Producedin | Mouse |
Purity | PurifiedwithProteinGaffinitychromatography |
Applications | Westernblot(WB)atasuggesteddilutionof1:2,0001:4,000.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | MANF(Mesencephalicastrocyte-derivedneurotrophicfactor). |
SpeciesAgainst | Human |
Form | PBSpH7.4,with0.1%sodiumazide. |
Storage | Storeat20°Cor-70°Cuponreceipt.Afteropeningmaintainundilutedinsmalleraliquotsat20°Cor-70°Cforupto6months.Avoidmultiplefreeze-thawcycles. |
ExpiryDate | Unopened,12monthsafterpurchase. |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。