Description | GFRα-4belongstotheGDNFreceptorfamily.Itisaglycosyl-phosphatidylinositol(GPI)-linkedcellsurfacereceptorforpersephin,andmediatesactivationoftheRETtyrosinekinasereceptor. |
Relatedproducts | C-1659-100ChickenantibodytoGFRalpha-1:affinitypurified;C-1660-100ChickenantibodytoGFRalpha-2:affinitypurified;C-1661-100ChickenantibodytoGFRalpha-3:affinitypurified; |
BatchNo. | Seeproductlabel |
Antigen | RecombinantHis-taggedhumanGFRa-4proteinproducedusingCHO-basedcellline.ForproductionofhGFRa-4,glycosylphosphatidyl-inositolGPI-anchorwasremovedandproteinwassecretedtothecellculturesupernatant.ProteinwaspurifiedbyNi-affinitychromatographyfollowinggel-filtrationfromcellculturesupernatant. |
Sequence | UniprotQ9GZZ7 |
AntibodyType | Polyclonal |
Isotype | IgY |
OtherNames | GDNFreceptoralpha-4,Persephinreceptor |
Accession | Q9GZZ7 |
Producedin | Chicken |
Purity | Affinitypurified |
Applications | WB,IHC.Adilutionof1:5000-1:10000isrecommendedforWesternblotsand1:1000to1:3000forimmunocytochemistry.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | HumanGFRa-4.Thisantibodydoesnotcross-reactwithhGFRa-1,hGFRa-2,hGFRa-3 |
SpeciesAgainst | Human |
AntibodyAgainst | GFRalpha-4 |
Blastit | Ifyouwouldliketousethisproductinanotherspeciesotherthanthosespecifiedhere,ortoseethesharedIDbetweentheimmunogenusedhereindifferentspeicesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis. |
Form | LiquidinPBSpH7.4containingnopreservatives |
Reconstitution | readytodiluteoncethawed |
Storage | Storeat-80°Cuponreceipt.Divideantibodyintoaliquotsuponreceipt.Avoidmultiplefreeze-thawcyclesasproductdegradationmayresult. |
ExpiryDate | 12monthsafterpurchase. |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。