产品编号：C-1659-100
市 场 价：¥7940.00
场 地：美国(厂家直采)
联系QQ：1570468124
电话号码：4000-520-616
邮 箱：
info@ebiomall.com
商品介绍
| Description | Glialcellline-derivedneurotrophicfactor(GDNF)andneurturin(NTN)aretwostructurallyrelated,potentneurotrophicfactorsthatplaykeyrolesinthecontrolofneuronsurvivalanddifferentiation.TheGFRα-1isamemberoftheGDNFreceptorfamily.Itisaglycosylphosphatidylinositol(GPI)-linkedcellsurfacereceptorforbothGDNFandNTN,andmediatesactivationoftheRETtyrosinekinasereceptor(www.ncbi.nlm.nih.gov/gene/2674). |
| Relatedproducts | C-1660-100chickenantibodytoGFRalpha-2:affinitypurified;C-1661-100chickenantibodytoGFRalpha-3:affinitypurified;C-1662-100chickenantibodytoGFRalpha-4:affinitypurified; |
| BatchNo. | Seeproductlabel |
| Unitsize | 100ug |
| Antigen | RecombinantHis-taggedhumanGFRalpha-1proteinproducedusingCHO-basedcellline.ForproductionofhGFRalpha-1,glycosylphosphatidyl-inositolGPI-anchorwasremovedandproteinwassecretedtothecellculturesupernatant.ProteinwaspurifiedbyNi-affinitychromatographyfollowinggel-filtrationfromcellculturesupernatant. |
| Sequence | UniprotP56159,wholemolecule |
| AntibodyType | Polyclonal |
| Isotype | IgY |
| OtherNames | RETligand1,TGF-betarelatedneurotrophicfactorreceptor1 |
| Accession | P56159 |
| Producedin | Chicken |
| MolecularWeight | ~63kDareducingconditions. |
| Purity | Affinitypurified |
| Applications | WB,ICC.Adilutionof1:5,000to1:10,000isrecommendedforWesternblotand1:1,000to1:2,000forImmunocytochemistry.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
| Specificity | HumanGFRalpha-1.NocrossreactionwithhGFRalpha-2,hGFRalpha-3,hGFRalpha-4 |
| SpeciesAgainst | Human |
| Blastit | Ifyouwouldliketousethisproductinanotherspeciesotherthanthosespecifiedhere,ortoseethesharedIDbetweentheimmunogenusedhereindifferentspeicesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis. |
| Form | ConcentratedammoniumsulphateinPBSpH7.4containingnopreservatives. |
| Reconstitution | Storeantibodystocksolutionat+4°Cuponreceipt.DONOTFREEZE.Thisproductisan(NH4)2SO4precipitate.Touse,mixwellbypipettingorvortexinggentlyprioruse,thenwithdrawthedesiredamountofantibodystocksolutionanddiluteintoyourantibodydilutionbufferandusenormally. Alternatively,materialcanbecentrifugedat10Kxgfor5minutesandtheliquidsulfatesolutioncarefullyremoved.ThenprecipitatedantibodycanberesUSPendedin0.1MP,250mMNaCL,pH7.4solution.Thesolutionshouldthenbedividedintoworkingaliquotsandstoredat-80Cuntilused.Preventmultiplefreezethawcyclesofaliquotsforbestproductlife. |
| Storage | Storeat+4°Cuponreceipt;DONOTFREEZE.Asproductis(NH4)2SO4(ammoniumsulfate)precipitate,mixwellbypipettingorvortexingpriortouse.Seereconstitutioninstructionsformoreinformation. |
| ExpiryDate | 12monthsafterpurchase |
品牌介绍
Biosensis专注于神经科学领域的抗体和试剂的开发，特别是神经营养因子和神经营养因子受体。 近30年来，Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子，我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症（AD）、帕金森氏症（PD）和肌萎缩侧索硬化（ALS）疾病，以及自噬和代谢应激障碍，包括肥胖、代谢综合征的研究、神经免疫学和炎症。
公司介绍
产品分类
TR-200-BG
PE-1243-50
Antibody Kits
PE-1246-5
TR-100-BG
S-1754-500
Neurotrophic Factors
Diabetes & Obesity
Intracellular Trafficking
PE-1239-5
Neuropeptides & Receptors
B-100-PS
Receptors & Channel Molecules
2 Plate ELISA kits
M-1763-100-FT
TR-200-BGT
PE-1239-2
PE-1242-5
M-1249-100
Neurotrophic Factor Receptors
Cell Cycle Regulators
S-1759-100
PE-1606-100
PE-1762-100
B-200-PS
PE-019-100
PE-1241-5
PE-003-100
1 Plate ELISA kits
BL-003-1000
PE-1246-2
Sensory Nervous System
PE-1253-100
TR-100-FJ
BL-005-500
Neuroendocrine
M-1728-100
DNA Damage & Repair
PE-001-100
PE-1608-1
TR-400-AG
PE-1243-25
Cell Markers
PE-1608-5
TR-100-FJT
Autophagy
PE-1242-2
Other Neuronal
Neurotransmitters & Enzymes
Antioxidant Enzymes
Neuronal Markers
Tag Antibodies
BL-004-500
PE-019-25
PE-1608-10
BL-002-1250
Receptor Body Chimeras
Signalling & Transcription
Matrix & Adhesion Molecules
BL-001-1250
Cancer
PE-019-500
Stem Cells
Junction Proteins
TR-300-AG
Apoptosis
PE-1252-100
Growth Factors
Development
Alzheimer\'s / Parkinson\'s
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