Description | Doc2-alphaismainlyexpressedinbrainandissuggestedtobeinvolvedinCa(2+)-dependentneurotransmitterrelease.Itmayalsobeinvolvedindynein-dependentintracellularvesicletransport.TheCDNApredictsa400-aminoacidproteinwithrelativemassof44,071Daand2repeatedC2-likedomainsintheC-terminalregion.TheC2domain1isinvolvedinbindingcalciumandphospholipids. Itispredominantlyexpressedinthebrainbutalsoexpressedintestis. |
BatchNo. | Seeproductlabel |
Unitsize | 50µl |
Antigen | RecombinanthumanDoc2-alpha(1-400)withaGSTtag. |
OtherNames | DoubleC2-likedomain-containingproteinalpha;Doc2;DOC2A |
Accession | DOC2A_HUMAN |
Producedin | Mouse |
Purity | Wholeserum |
Applications | ThisantibodyisrecommendedforWBandELISA.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | SpecificityhasbeenconfirmedbyWBanddirectELISAagainsttheantigen. |
Cross-reactivity | Human.Otherspecieshavenotbeentested. |
Blastit | Toseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequencethatyouareinterestedinandcopyandpasteitHEREandblast/formatit. |
Form | Liquid.50%glycerol |
Storage | Keepaliquotsat-20ºCforhigherstABIlityorat4ºCwithanappropriateantibacterialagent.Avoidrepetitivefreeze/thawcycles. |
ExpiryDate | 12monthsafterpurchase |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。