Description | Tachykininsareactivepeptideswhichexciteneurons,evokebehaviouralresponses,arepotentvasodilatorsandsecretagogues,andcontractmanysmoothmuscles.Tachykinin-3isasecretedproteinanditsexpressionduringpregnancyisconfinedtotheoutersyncytiotophoblastoftheplacenta.PlasmaconcentrationsofTachykinin-3aregrosslyelevatedinpregnancy-inducedhypertensionandpre-eclampsia. |
BatchNo. | Seeproductlabel |
Unitsize | 100µg |
Antigen | TAC3(17-121aa)full-lengthrecombinanthumanTachykininproteinwithGSTtag. |
Isotype | IgG1kappa |
Clone | 2D7 |
OtherNames | ZNEUROK1;NeurokininB;TAC3;NKNB |
Accession | TKNK_HUMAN |
Producedin | Mouse |
Purity | ProteinGpurifiedimmunoglobulin |
Applications | ThisantibodyisrecommendedforWBandELISA.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | SpecificityhasbeenconfirmedbyWBanddirectELISAagainsttheantigen. |
Cross-reactivity | Human.RatandmousesampleswerenegativebyIHC.Otherspecieshavenotbeentested. |
Blastit | Toseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequencethatyouareinterestedinandcopyandpasteitHEREandblast/formatit. |
Form | LyophilisedfromPBSpH7.4 |
Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Afterreconstitutionkeepaliquotsat-20ºCforhigherstABIlityorat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforadditionalstability.Avoidrepetitivefreeze/thawcycles. |
ExpiryDate | 12monthsafterpurchase |
SpecificReferences | SkrapitsKetal.(2015)"Neuropeptideco-expressioninhypothalamickisspeptinneuronsoflaboratoryanimalsandthehuman."FrontNeurosci.Feb;9:29. BorsayBÁetal.(2014)"Hypophysiotropicgonadotropin-releasinghormoneprojectionsareexposedtodenseplexusesofkisspeptin,neurokininBandsubstancepimmunoreactivefibersinthehuman:astudyontissuesfrompostmenopausalwomen."Neuroendocrinology.2014;100(2-3):141-52. |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。