Description | FUNCTION:Neuropeptidesthatplayasignificantroleintheregulationoffoodintakeandsleep-wakefulness,possIBLybycoordinatingthecomplexbehavioralandphysiologicresponsesofthesecomplementaryhomeostaticfunctions.Abroaderroleinthehomeostaticregulationofenergymetabolism,autonomicfunction,hormonalbalanceandtheregulationofbodyfluids,isalsosuggested.Orexin-AbindstobothOX1RandOX2Rwithahighaffinity,whereasorexin-BbindsonlytoOX2Rwithasimilarhighaffinity.SUBCELLULARLOCATION:Endoplasmicreticulum;roughendoplasmicreticulum.Associatedwithperikaryalroughendoplasmicreticulumaswellascytoplasmiclargegranularvesiclesatsynapses.SIMILARITY:Belongstotheorexinfamily. |
BatchNo. | Seeproductlabel |
Unitsize | 100µl |
Antigen | ApeptidefromtheN-terminusofhumanOrexinA(1-13aa). |
Sequence | AQPLPDCCRQKTC |
OtherNames | Orexin;Hypocretin;Hcrt;Hypocretin-1;HCRT;OX;PPORX;PPOX; |
Accession | O43612OREX_HUMAN; |
Producedin | Chicken |
Applications | ELISA.Suggesteddilutionat1:2,000to1:5,000asadetectionantibodyand1:200to1:1,000asacoatingantibodyinsandwichELISA.Biosensisrecommendsthattheoptimalworkingdilutionshouldbedeterminedbytheenduser. |
Cross-reactivity | Human,Mouse,Rat |
BlastURL | Clickhere |
Form | Liquid.PBSwith0.02%SodiumAzide |
Storage | Shorttermstorageat2-8°Cforoneweek.At-20°Casanundilutedliquidforupto12months. |
ExpiryDate | 12monthsafterpurchase |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。