Description | Ghrelinistheligandforgrowthhormonesecretagoguereceptortype1(GHSR)anduponbindingtothereceptoritinducesthereleaseofgrowthhormonefromthepituitary.Thisligandhasanappetite-stimulatingeffectandisinvolvedingrowthregulation. |
BatchNo. | Seeproductlabel |
Unitsize | 50µl |
Antigen | Asyntheticpeptide(GSSFLSPEHQRVQQRKESKKPPAKLQPR)correspondingtotheaminoacids24-51fromhumanghrelin.Thispeptidewasconjugatedtocarrierproteintoenhancetheimmunologicalresponse. |
OtherNames | Appetite-regulatinghormone;Growthhormonesecretagogue;Growthhormone-releasingpeptide;Motilin-relatedpeptide;M46protein |
Accession | GHRL_HUMAN |
Producedin | Guineapig |
Purity | Neatserum. |
Applications | IHC.Aconcentrationof1in3000isrecommendedforIHC.IHCperformedinsheepabomasumdemonstratesintensestainingofcellsandterminals.Nostainingisevidentwhentheprimaryantibodyispre-absorbedwith0.5mg/mlofhumanghrelin.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | Specificitywasdemonstratedbyimmunohistochemistry. |
Cross-reactivity | Thisantibodyisknowntoreactwithsheepandhuman.Otherspecieshavenotyetbeentested. |
Blastit | Ifyouwouldliketoseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequence(makesurethatyouareselectingthesequencethatyouareinterestedin,asthesequencemaybetheprecursorratherthanthematureproteinforexample)andcopyandpasteitHEREandblast/formatit. |
Form | Lyophilised |
Reconstitution | Reconstitutein50µlsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Itisrecommendedthatathawedsampleisstoredat4°Cfornolongerthan2weeks.Allocationofappropriateanti-bacterialagentcanincreaseshelflifebyseveralweeks.Dilutedserumshouldbepreparedasrequired.LongtermstABIlityrequiresstorage,preferablyinsmallaliquotsat-20°Corlower.Glycerol(1:1)canbeaddedtoneatserumforadditionalstabilityifintendedusedoesnotpreventthis. |
ExpiryDate | 12monthsuponreconstitution. |
References | KojimaM,HosodaH,MatsuoH,KangawaK(2001).Ghrelin;discoveryofthenaturalendogenousligandforthegrowthhormonesecretagoguereceptor.TrendsEndocrinolMetab12pp118-122. |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。