Description | Luteinizinghormonepromotesspermatogenesisandovulationbystimulatingthetestesandovariestosynthesizesteroids.ItexistsasaheterodimerofacommonalphachainandauniquebetachainwhichconfersBIOLOGicalspecificitytothyrotropin,lutropin,follitropin,andgonatropin. |
BatchNo. | Seeproductlabel |
Unitsize | 50µl |
Antigen | AsyntheticpeptidecorrespondingtotheantigenicregionwithintheovineLHresidue. |
OtherNames | Lutropinsubunitbeta[Precursor];Luteinizinghormonesubunitbeta;LSH-beta;LSH-B;LH-B;Lutropinbetachain;Interstitialcell-stimulatinghormone |
Accession | LSHB_SHEEP |
Producedin | Guineapig |
Purity | Neatserum. |
Applications | IHC.Aconcentrationof1in3000isrecommendedforIHC.IHCperformedinsheeppituitarydemonstratesintensestainingofcells.Nostainingisevidentwhentheprimaryantibodyispre-absorbedwith0.5mg/mlofLH.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | Specificitywasdemonstratedbyimmunohistochemistry. |
Cross-reactivity | Thisantibodyisknowntoreactwithsheep.Otherspecieshavenotyetbeentested |
Blastit | Ifyouwouldliketoseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequence(makesurethatyouareselectingthesequencethatyouareinterestedin,asthesequencemaybetheprecursorratherthanthematureproteinforexample)andcopyandpasteitHEREandblast/formatit. |
Form | Lyophilised |
Reconstitution | Reconstitutein50µlsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Itisrecommendedthatathawedsampleisstoredat4ºCfornolongerthan2weeks.Allocationofappropriateanti-bacterialagentcanincreaseshelflifebyseveralweeks.Dilutedserumshouldbepreparedasrequired.LongtermstABIlityrequiresstorage,preferablyinsmallaliquotsat-20ºCorlower.Glycerol(1:1)canbeaddedtoneatserumforadditionalstabilityifintendedusedoesnotpreventthis. |
ExpiryDate | 12monthsuponreconstitution. |
SpecificReferences | SanchezNS,QuinnKE,AshleyAK,AshleyRL(2017).Intheovinepituitary,CXCR4islocalizedingonadotropesandsomatotropesandincreaseswithelevatedserumprogesterone.DomestAnimEndocrinol.Inpress. |
References | ClarkeIJ,TobinVA,PompoloS,PereiraA(2005).EffectsofchangingGonadotropin-releasinghormonepulsefrequencyandestrogentreatmentonlevelsofestrADIolreceptoralphaandinductionofFosandphosphorylatedcyclicadenosinemonophosphateresponseelementbindingproteininpituitarygonadotropes:studiesinhypothalamo-pituitarydisconnectedewes.Endocrinology146(3)pp.1128-1137. |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。