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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Rabbit polyclonal antibody to Internexin alpha: Whole serum/R-1379-50/50 µl
产品编号:R-1379-50
市  场 价:¥5940.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$297.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Rabbit polyclonal antibody to Internexin alpha: Whole serum/R-1379-50/50 µl
商品介绍
DescriptionNeurofilamentscanbedefinedastheintermediateor10nmdiameterfilamentsfoundinneuronalcells.Theyarecomposedamixtureofsubunitswhichoftenincludestheneurofilamenttripletproteins,NF-L,NF-MandNF-H.Neurofilamentsmayalsoincludeperipherin,alpha-internexin,nestinandinsomecasesvimentin.Alpha-internexinisa~66kDaClassIVintermediatefilamentsubunitexpressedinlargeamountsearlyinneuronaldevelopment,butisdownregulatedinmanyneuronsasdevelopmentprocedes.Manyclassesofmatureneuronscontainalpha-internexininadditiontoNF-L,NF-MandNF-H.Insomematureneuronsalpha-internexinistheonlyneurofilamentsubunitexpressed.Antibodiestoalpha-internexinarethereforeuniqueprobestostudyandclassifyneuronaltypesandfollowtheirprocessesinsectionsandintissueculture.Inadditiontheveryearlydevelopmentalexpressionofalpha-internexinmeansitspresenceisanearlyandconvenientdiagnosticfeatureofneuronalProgenitorscellsandothercellcommittedtotheneuronallineage.
BatchNo.Seeproductlabel
Unitsize50µl
AntigenRecombinantalpha-internexinexpressedandpurifiedfromE.coli
AntibodyTypeAntiserum
OtherNames67kDaneurofilamentprotein;NF-66;Neurofilament-66;Alpha-internexin;Alpha-Inx;Neurofilament5;INA;NEF5;
AccessionQ16352AINX_HUMAN;P23565AINX_RAT;
ProducedinRabbit
ApplicationsWesternBlotting(WB)andImmunocytochemistry(IC).Adilutionof1:10,000-20,000isrecommendedforWB.Adilutionof1:500-1,000isrecommendedforIC.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyWB.Thisantibodyisspecificforthe64-66kDaalpha-internexinprotein.Molecularweightwilldependonspecies.
AntibodyAgainstInternexinalpha
Cross-reactivityHu,Rat,Ms,Fel,andothermammals
BlastURLClickhere
FormLyophilised
AppearanceWhitepowder
ReconstitutionReconstituteinsteriledistilledwater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionoflyophilisedantibody,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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