Description | Protocadherin alpha-2 is 1 of 15 tandemly arranged genes within the PCDHA gene cluster. These 15 N-terminal 'variable' exons are individually spliced to a downstream C-terminal constant region to form distinct PCDHA transcripts. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain.The PCDH proteins are cadherin-like cell surface proteins that are expressed in neurons and are present at synaptic junctions. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. |
Batch No. | See product label |
Unit size | 50 µl |
Antigen | Partial recombinant human PCDH-alpha-2 (189-282) with a GST tag. |
Other Names | PCDH-alpha-2; PCDHA2 |
Accession | PCDA2_HUMAN |
Produced in | Mouse |
Purity | Whole serum |
Applications | This antibody is recommended for WB and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user. |
Specificity | Specificity has been confirmed by WB and direct ELISA against the antigen. |
Cross-reactivity | Human. Other species have not been tested. |
Blast it | To see the shared identity between different species or other proteins, follow the link in the Accession field, select the sequence that you are interested in and copy and paste it HERE and blast/format it. |
Form | Liquid. 50% glycerol |
Storage | Keep aliquots at -20ºC for higher stability or at 4ºC with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles. |
Expiry Date | 12 months after purchase |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。