请使用支持JavaScript的浏览器!
主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Mouse monoclonal antibody to Internexin alpha [1D2]/M-1378-250/250 µl
产品编号:M-1378-250
市  场 价:¥5940.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$297.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Mouse monoclonal antibody to Internexin alpha [1D2]/M-1378-250/250 µl
商品介绍
DescriptionNeurofilamentscanbedefinedastheintermediateor10nmdiameterfilamentsfoundinneuronalcells.Theyarecomposedamixtureofsubunitswhichoftenincludestheneurofilamenttripletproteins,NF-L,NF-MandNF-H.Neurofilamentsmayalsoincludeperipherin,alpha-internexin,nestinandinsomecasesvimentin.Alpha-internexinisa~66kDaClassIVintermediatefilamentsubunitexpressedinlargeamountsearlyinneuronaldevelopment,butisdownregulatedinmanyneuronsasdevelopmentprocedes.Manyclassesofmatureneuronscontainalpha-internexininadditiontoNF-L,NF-MandNF-H.Insomematureneuronsalpha-internexinistheonlyneurofilamentsubunitexpressed.Antibodiestoalpha-internexinarethereforeuniqueprobestostudyandclassifyneuronaltypesandfollowtheirprocessesinsectionsandintissueculture.Inadditiontheveryearlydevelopmentalexpressionofalpha-internexinmeansitspresenceisanearlyandconvenientdiagnosticfeatureofneuronalProgenitorscellsandothercellcommittedtotheneuronallineage.
BatchNo.Seeproductlabel
Unitsize250µl
AntigenRecombinantratalpha-internexinexpressedandpurifiedfromE.coli
AntibodyTypeMonoclonal
IsotypeIgG1
Clone1D2
OtherNames66kDaneurofilamentprotein;NF-66;Neurofilament-66;Alpha-internexin;Alpha-Inx;Neurofilament5;INA;NEF5;
AccessionQ16352AINX_HUMAN;P23565AINX_RAT;
ProducedinMouse
ApplicationsWesternBlotting(WB),Immunocytochemistry(IC)andImmunohistochemistryonparaffinsections(IHC).TherecommendeddilutionforWBis1:5000-10,000.TheepitoperecognisedbythisantibodyisintheC-terminalnon-helicalextensionoftheproteinandisunusuallyresistanttoaldehydefixationsothisantibodyisideallysuitedforstudiesofparaffinembeddedformalinfixedhistologicalsections.TherecommendeddilutionforIHCis1:1,000-5,000.ForIC,dilutionis1:250-500.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyWB.Thisantibodyisspecificforthe64-66kDaalpha-internexinprotein.Molecularweightwilldependonspecies.
AntibodyAgainstInternexinalpha
Cross-reactivityHu,Rat,Ms,Fel,andothermammals
BlastURLClickhere
FormLyophilisedwith5%trehalose
AppearanceWhitepowder
ReconstitutionReconstituteinsteriledistilledwater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionoflyophilisedantibody,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

自营商城图标
厂家直采
全球直采 正品优价
正品保障图标
正品保障
厂家直发 有线跟踪
解放采购图标
正规清关
CIF100%正规报关,提供发票
及时交付图标
及时交付
限时必达 不达必赔