Description | Arc(alsotermedactivity-regulatedCytoskeleton-associatedproteinorArg3.1),isaneffectorimmediateearlygenewhoseupregulationhasbeendemonstratedduringeventsofsynapticplasticity.Arg3.1expressionisdetectableinneuronalcellbodiesanddendritesinthebrainregionsincludingstriatumandcortexhippocampus,hypothalamus,amygdala. |
BatchNo. | Seeproductlabel |
Unitsize | 100µl |
Antigen | AsyntheticpeptidefromtheCterminalofhumanArg3.1protein(ARCprotein)conjugatedtoBlueCarrierProtein.ThesequenceishomologouswithmouseandratformofArg3.1. |
OtherNames | ARC;activityregulatedcytoskeletal-associatedprotein;Activity-regulatedgene3.1proteinhomolog;Arg3.1;RCA/ARG3.1;ARC; |
Accession | ARC_HUMAN ARC_MOUSE ARC_RAT |
Producedin | Rabbit |
Purity | Wholeserum |
Applications | IHC.Adilutionof1:50to1:1000isrecommended.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | SpecificforArg3.1. |
Cross-reactivity | RatandMouse.Otherspeciesnotyettested. |
Form | Lyophilised,containingnopreservatives |
Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.Usesterilemethodsasantibodydoesnotcontainpreservatives |
Storage | Afterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity.Glycerol(1:1)maybeaddedforanadditionalstability.Sodiumazideorotherappropriateantibacterialagentshouldbeaddedifmaterialistobekeptanylengthoftimeat4ºC.Avoidrepetitivefreeze/thawcycles. |
ExpiryDate | 12monthsafterpurchase |
References | 1.KajiyaK,etal.J.Neurosci.21:6018-6025(2001). 2.YoungJ.M,etal.GenomeBiol.4:RESEARCH71.1-RESEARCH71.13(2003). 3.ZhangX.,FiresteinS.Nat.Neurosci.5:124-133(2002). 4.YoungJ.M,etal.Hum.Mol.Genet.11:535-546(2002). 5.KellyMP,etal.Neuroscience.110(4):617-26(2002). |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。