商品介绍
| Description | Arc (also termed activity-regulated cytoskeleton-associated protein or Arg3.1), is an effector immediate early gene whose upregulation has been demonstrated during events of synaptic plasticity. Arg3.1 expression is detectable in neuronal cell bodies and dendrites in the brain regions including striatum and cortex hippocampus, hypothalamus, amygdala. |
| Batch No. | See product label |
| Unit size | 500 µg |
| Antigen | A synthetic peptide from the C terminal of human Arg3.1 protein (ARC protein) conjugated to Blue Carrier Protein. The sequence is homologous with mouse and rat form of Arg3.1. |
| Other Names | ARC; activity regulated cytoskeletal-associated protein; Activity-regulated gene 3.1 protein homolog; Arg3.1; RCA/ARG3.1; ARC; |
| Accession | Arg3.1_HUMAN
Arg3.1_MOUSE Arg3.1_RAT |
| Produced in | Rabbit |
| Purity | Protein G purified IgG |
| Applications | IHC. A concentration of of 2-4 µg/ml is recommended for this application. Biosensis recommends optimal dilutions/concentrations should be determined by the end user. |
| Specificity | Specific for Arg3.1. |
| Cross-reactivity | Rat and Mouse. Other species not yet tested. |
| Form | Lyophilised |
| Reconstitution | Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage | After reconstitution keep aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles. |
| Expiry Date | 12 months after purchase |
| References | 1. Kajiya K, et al. J. Neurosci. 21:6018-6025(2001).
2. Young J.M, et al. Genome Biol. 4:RESEARCH71.1-RESEARCH71.13(2003). 3. Zhang X., Firestein S. Nat. Neurosci. 5:124-133(2002). 4. Young J.M, et al. Hum. Mol. Genet. 11:535-546(2002). 5. Kelly MP, et al. Neuroscience. 110(4):617-26 (2002). |
品牌介绍
Biosensis专注于神经科学领域的抗体和试剂的开发，特别是神经营养因子和神经营养因子受体。 近30年来，Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子，我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症（AD）、帕金森氏症（PD）和肌萎缩侧索硬化（ALS）疾病，以及自噬和代谢应激障碍，包括肥胖、代谢综合征的研究、神经免疫学和炎症。
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