Description | H2AXbelongstothehistoneH2Afamily.ThefourcorehistonesinvolvedintheformationofthenucleosomestructureofcompactedchromatinareH2A,H2B,H3,andH4.H2AXisphosphorylatedonSer-140toformgamma-H2AXinresponsetoDNAdouble-strandbreaks. |
BatchNo. | Seeproductlabel |
Unitsize | 100µg |
Antigen | Syntheticpeptidefromaregionsurroundingphosphorylatedserine140ofhumanH2AX(134-143aa). |
Sequence | KKATQASQEY |
OtherNames | H2AX139ph;HistoneH2A.x;H2a/x;H2AFX;H2AX;HistoneH2AX;HistoneH2AFX;HistoneH2A/X;gammaH2AX; |
Accession | P16104H2AX_HUMAN; |
Producedin | Rabbit |
Applications | WesternBlottingatasuggesteddilutionof1:1,000,FlowCytometry(2ug/10^6cells).Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
SpeciesAgainst | Human; |
Cross-reactivity | ThisantiserumdetectsphosphorylatedH2AXonly. |
BlastURL | Clickhere |
Form | Lyophilised |
Reconstitution | Reconstitutein100µlofsteriledistilledwater.Centrifugetoremoveanyinsolublematerial. |
Storage | Atleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlityandat4°Cwithanappropriateantibacterialagent.Avoidfreeze-thawcycles. |
ExpiryDate | 12monthsafterpurchase |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。