| Description | C-reactiveproteinhasseveralrolesassociatedwithhostdefencesuchas;promotingagglutination,bacterialcapsularswelling,phagocytosisandcomplementfixationthroughitscalcium-dependentbindingtophosphorylcholine.ItcaninteractwithDNAandhistonesandmayscavengenuclearmaterialreleasedfromdamagedcirculatingcells.COFACTOR:Binds2calciumionspersubunit.C-reactiveproteinexistsasahomopentamer.Pentaxin(orPentraxin)haveadiscoidarrangementof5non-covalentlyboundsubunits.Thereare2alternativelysplicedisoforms.C-reactiveproteinisfoundinplasmaanditsconcentrationincreasesgreatlyduringacutephaseresponsetotissueinjury,infectionorotherinflammatorystimuli.ItisinducedbyIL-1andIL-6. |
| BatchNo. | Seeproductlabel |
| Unitsize | 100µl |
| Antigen | HumanrecombinantC-Reactiveprotein |
| OtherNames | CRP;PTX1 |
| Accession | CRP_HUMAN |
| Producedin | Sheep |
| Purity | Wholeserum |
| Applications | WB.Extremelyhightitreantibody.Forwesternblotadilutionof1:10,000to1:100000isrecommended.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
| Specificity | IthasbeenshowntobespecificforC-reactiveproteinbyWB. |
| Cross-reactivity | Human,otherspecieshavenotyetbeentested. |
| Blastit | IfyouwouldliketoseethesharedidentitybetweendifferentspeciesorotherproteinsfollowthelinkinAccessionfield,selectthenthesequence(makesurethatyouareselectingthesequencethatyouareinterestedin,asthesequencemaybetheprecursorratherthanthematureproteinforexample)andcopyandpasteitHEREandblast/formatit. |
| Form | Lyophilisedwith0.01%Thimerosal |
| Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
| Storage | Afterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent. |
| ExpiryDate | 12monthsafterpurchase |
| References | 1.LeiK.-J,etal.J.Biol.Chem.260:13377-13383(1985). 2.WooP,etal.J.Biol.Chem.260:13384-13388(1985). |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。



