Description | Inthepresenceofcalciumions,SurfactantProteinAbindstosurfactantphospholipidstolowerthesurfacetensionattheair-liquidinterfaceinthealveoliofthemammalianlungandisessentialfornormalrespiration(Ref:SWISSPROT). |
BatchNo. | Seeproductlabel |
Unitsize | 100µg |
Antigen | Asyntheticpeptidecorrespondingtoaregion(221-236aa)fromhumanSurfactantProteinA. |
AntigenLocation | 221-236 |
OtherNames | Pulmonarysurfactant-associatedproteinA1;PSP-A;PSPA;SP-A;SP-A1;SP-A2;35kDapulmonarysurfactant-associatedprotein;Alveolarproteinosisprotein;Collectin-4;Collectin-5;SFTPA1;SFTPA2;COLEC4;PSAP;SFTP1;SFTPA;SFTPA1B;SFTPA2B; |
Accession | Q8IWL2SFTA1_HUMAN;Q8IWL1SFPA2_HUMAN; |
Producedin | Rabbit |
Applications | WesternBlotting(WB).Aconcentrationof0.1-0.5µg/mlisrecommendedforWB.HumanSurfactantproteinA(precursor)hasapredictedlengthof248aminoacidsandMWof26kDa..Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | ThespecificityofthisantibodyhasbeenconfirmedbyWBagainsttheantigen. |
AntibodyAgainst | SurfactantProteinA |
Cross-reactivity | Human;rat;predictedtoreactwithmouseduetosequencehomology |
Blastit | Ifyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenproteins.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample. |
BlastURL | Clickhere |
Form | Liquid(0.5ml).50%glycerol,0.9mgNaCland0.2mgNa2HPO4 |
Reconstitution | TheliquidformulationshouldbedilutedinPBS(pH7.4) |
Storage | Atleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles. |
ExpiryDate | 12monthsafterpurchase |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。