Description | Thisproductisnolongeravailable.Pleaseseebelowforourrecommendedalternativeproducts.
Replacedby | R-1730-100 | BatchNo. | Seeproductlabel | Unitsize | 100µg | Antigen | Asyntheticpeptide(TAVHLGQCVTCSDKQY)correspondingtoaregion(16-31)fromtheN-terminusofmouseCD40. | OtherNames | Tumournecrosisfactorreceptorsuperfamilymember5;CD40Lreceptor;Bp50;TNFRSF5; | Accession | P27512TNR5_MOUSE;Q4QQW2Q4QQW2_RAT | Producedin | Rabbit | Purity | Affinitypurifiedonantigencolumn | Applications | WesternBlotting(WB).Aconcentrationof1.0-2.0µg/mlisrecommendedforWB.ThepredictedlengthofmouseCD40is289residuesandaMWof32kDa.Theobservedbandsizeisapproximately45kDa.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. | Specificity | ThespecificityofthisantibodyhasbeenconfirmedbyWBagainsttheantigen. | Cross-reactivity | Mouse;rat;rabbit; | Blastit | Ifyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechosecarefully,asthesequenceyouchosemaybeaprecursorratherthanthematureproteinforexample. | Form | Liquid(0.5ml).50%glycerol,0.9mgNaCland0.2mgNa2HPO4 | Reconstitution | TheliquidformulationshouldbedilutedinPBS(pH7.4) | Storage | Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles. | ExpiryDate | 12monthsafterpurchase | References | KeZ.J.etal.CD40-CD40Linteractionspromoteneuronaldeathinamodelofneurodegenerationduetomildimpairmentofoxidativemetabolism.NeuRochemInt.2005Aug;47(3):204-15. | 品牌介绍
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。
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