![Biosensis/Mouse monoclonal antibody to Neurofilament Medium [3H11]/M-1394-100/100 µl](images/biosensis/201712/M-1394-100_merged.jpg)
产品编号：M-1394-100
市 场 价：¥5940.00
场 地：美国(厂家直采)
联系QQ：1570468124
电话号码：4000-520-616
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info@ebiomall.com
商品介绍
| Description | Neurofilaments are composed of three intermediate filament proteins: light (~68 kDa), medium (~160 kDa) and heavy (~200 kDa), which are involved in the maintenance of the neuronal caliber. Neurofilament medium runs on SDS-PAGE gels in the range 145-170 kDa, with some variation in different species. |
| Batch No. | See product label |
| Unit size | 100 µl |
| Antigen | Raised against a recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E. coli. The epitope is localized to within the last 56 amino acids at the extreme C-terminus of rat NF-M, the so-called KE segment which is highly conserved between NF-M molecules from different species. |
| Antibody Type | Monoclonal |
| Isotype | IgG1 |
| Clone | 3H11 |
| Other Names | Neurofilament medium polypeptide; NF-M; 160 kDa neurofilament protein; Neurofilament 3; Neurofilament triplet M protein; Nefm; Nef3; Nfm; |
| Accession | P12839 NFM_RAT; |
| Produced in | Mouse |
| Applications | Western Blotting (WB), Immunocytochemistry (IC), Immunohistochemistry (IH) and Flow Cytometry. A dilution of 1:1,000 - 1:5,000 is recommended for WB. A dilution of 1:100 - 1:500 is recommended for IC and IH. Biosensis recommends optimal dilutions/concentrations should be determined by the end user. |
| Specificity | Specifically recognizes the medium neurofilament subunit NF-L in WB. |
| Antibody Against | Neurofilament Medium |
| Cross-reactivity | Hu, Rat, Ms, Fel, Bov, Por, Chk |
| Blast URL | Click here |
| Form | Lyophilised with 5% trehalose |
| Appearance | White powder |
| Reconstitution | Reconstitute in sterile distilled water. Centrifuge to remove any insoluble material. |
| Storage | After reconstitution of lyophilised antibody, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles. |
| Expiry Date | 12 months after purchase |
| Specific References | 1. Felitsyn N. et al (2008) The heme precursor delta-aminolevulinate blocks peripheral myelin formation. J Neurochem. 2008 Sep;106(5):2068-79.
|
品牌介绍
Biosensis专注于神经科学领域的抗体和试剂的开发，特别是神经营养因子和神经营养因子受体。 近30年来，Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子，我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症（AD）、帕金森氏症（PD）和肌萎缩侧索硬化（ALS）疾病，以及自噬和代谢应激障碍，包括肥胖、代谢综合征的研究、神经免疫学和炎症。
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