Biosensis/Mouse monoclonal antibody to NeuN/Fox3 [1B7] (1-99): IgG/M-377-100/100 µL,Biosensis,,Biosensis,Biosensis inc,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Biosensis/Mouse monoclonal antibody to NeuN/Fox3 [1B7] (1-99): IgG/M-377-100/100 µL

产品编号：M-377-100

市场价：¥5940.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$297.00

品牌： Biosensis

公司：Biosensis

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商品介绍

Description	Fox3 is one of a family of mammalian homologues of Fox-1. The Fox proteins are about 46kDa in size, and each includes a central highly conserved RRM type RNA recognition motif. Much interest has focused on Fox3 as a result of the recent finding that this protein corresponds to NeuN, a neuronal nuclear antigen. NeuN/Fox-3 has a function in RNA splicing and is expressed heavily and specifically in neuronal nuclei and cytoplasm. Our antibody was raised against the N-terminal 100 amino acids of human Fox3 as expressed in and purified from E. coli. We did not use full length Fox3 as immunogen since the three mammalian Fox homologues, namely Fox1, Fox2 and Fox3, include virtually identical RRM motifs. The N-terminal region of the three molecules are much more variable in the three molecules so antibodies specific for each of the three molecules can therefore be generated.
Batch No.	See product label
Unit size	100 µL
Antigen	Antibody was raised against the N-terminal 100 amino acids of human Fox3 as expressed in and purified from E. coli.
Sequence	MAQPYPPAQYPPPPQNGIPAEYAPPPPHPTQDYSGQTPVPTEHGMTLYTPAQTHPEQPGS EASTQPIAGTQTVPQTDEAAQTDSQPLHPSDPTEKQQPKR
Antigen Location	1-99
Antigen Length	100
Antibody Type	Monoclonal
Isotype	IgG2a
Clone	1B7
Other Names	Feminizing locus on X; Fox-1; Fox3; NeuN;
Accession	A6NFN3 FOX1C_HUMAN;
Produced in	Mouse
Applications	Western Blotting (WB) and Immunocytochemistry (IC). A dilution of 1:5,000 - 1:10,000 is recommended for WB. A dilution of 1:500 - 1:1,000 is recommended for IC. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Specificity	The specificity of this antibody has been confirmed by WB. Two alternate transcripts can be seen at 46 kDa and 48 kDa.
Antibody Against	NeuN/Fox3
Cross-reactivity	Hu, Rat, Ms, Bov, Porcine
Blast URL	Click here
Form	Lyophilised with 5% trehalose, without preservatives.
Appearance	White powder
Reconstitution	Reconstitute in sterile distilled water. Centrifuge to remove any insoluble material.
Storage	After reconstitution of lyophilised antibody, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
Expiry Date	12 months after purchase
Specific References	Hamanoue M et al., (2016) "Cell-permeable p38 MAP kinase promotes migration of adult neural stem/progenitor cells" Sci Rep. 6:24279. Application: Western Blotting. Species: Mouse Han YC et al., (2016) "Direct Reprogramming of Mouse Fibroblasts to Neural Stem Cells by Small Molecules" Stem Cells Int. 2016; 2016:4304916. Application: IF. Species: Mouse Han YC & Zhou XF, (2015) "Method of producing multipotent stem cells" US 20150322405 A1 (patent). Application: IF. Species: Human

品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发，特别是神经营养因子和神经营养因子受体。 近30年来，Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子，我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症（AD）、帕金森氏症（PD）和肌萎缩侧索硬化（ALS）疾病，以及自噬和代谢应激障碍，包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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