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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Chicken polyclonal antibody to Neurofilament Medium/C-1393-50/50 µl
产品编号:C-1393-50
市  场 价:¥5940.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$297.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Chicken polyclonal antibody to Neurofilament Medium/C-1393-50/50 µl
商品介绍
DescriptionNeurofilamentsarecomposedofthreeintermediatefilamentproteins:light(~68kDa),medium(~160kDa)andheavy(~200kDa),whichareinvolvedinthemaintenanceoftheneuronalcaliber.NeurofilamentmediumrunsonSDS-PAGEgelsintherange145-170kDa,withsomevariationindifferentspecies.
BatchNo.Seeproductlabel
Unitsize50µl
AntigenRecombinantfusionproteincontainingtheextremeC-terminalsegmentofratNF-M.
IsotypeIgY
OtherNamesNeurofilamentmediumpolypeptide;NF-M;160kDaneurofilamentprotein;Neurofilament3;NeurofilamenttripletMprotein;Nefm;Nef3;Nfm;
AccessionP12839NFM_RAT;
ProducedinChicken
ApplicationsWesternBlotting(WB)andImmunocytochemistry(IC).Adilutionof1:5,000-1:10,000isrecommendedforWB.Adilutionof1:1,000-1:2,000isrecommendedforIC.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificitySpecificallyrecognizesthemediumneurofilamentsubunitNF-LinWB.Bandappearsat~145kDainWBfromrodentand~160kDaforhumanandbovineWB.
AntibodyAgainstNeurofilamentMedium
Cross-reactivityHu,Rat,Ms,Fel,Chk.Predictedtoreactwithothermammaliantissuesduetosequencehomology.
BlastURLClickhere
FormLyophilisedwith5%trehalose
AppearanceWhitepowder
ReconstitutionReconstituteinsteriledistilledwater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionoflyophilisedantibody,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase
SpecificReferences1.JarjourA.A.etal(2007)Maintenanceofaxo-oligodendroglialparanodaljunctionsrequiresDCCandnetrin-1.JNeurosci.2008Oct22;28(43):11003-14.
2.RangarajuS.etal(2009)Moleculararchitectureofmyelinatedperipheralnervesissupportedbycalorierestrictionwithaging.AgingCell.2009Apr;8(2):178-91.
3.PearseD.D.etal(2007)TransplantationofSchwanncellsand/orolfactoryensheathinggliaintothecontusedspinalcord:Survival,migration,axonassociation,andfunctionalrecovery.Glia.2007Jul;55(9):976-1000.
4.ShawG.etal(2004)CharacterizationofthebovineneurofilamentNF-MproteinandCDNAsequence,andidentificationofinvitroandinvivocalpaincleavagesites.BiochemBiophysResCommun.2004Dec10;325(2):619-25.
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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