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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Rabbit polyclonal antibody to mouse elF2c (Ago2) protein (845-860): Affinity purified/R-1556-100/100 µl
产品编号:R-1556-100
市  场 价:¥5940.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$297.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Rabbit polyclonal antibody to mouse elF2c (Ago2) protein (845-860): Affinity purified/R-1556-100/100 µl
商品介绍
DescriptionTheelF2c(Argonaute,Ago)proteinisacoreproteinoftheRNA-inducedsilencingcomplex(RISC).
BatchNo.Seeproductlabel
Unitsize100µl
AntigenAsyntheticpeptidecorrespondingtoasequence(845-860aa)fromtheC-terminusofmouseelF2CconjugatedtoKLH.
SequenceC-KAVQVHQDTLRTMYFA
AntigenLocation845-860aa(eIF-2C2)
OtherNamesProteinargonaute-1;Proteinargonaute-2;Proteinargonaute-3;Argonaute1;Argonaute2;Argonaute3;mAgo1;mAgo2;Eukaryotictranslationinitiationfactor2C;eIF-2C2;eIF-2C1;eIF2C2;Piwi/argonautefamilyproteinmeIF2C2Proteinslicer;Eif2c2;Ago1;Ago2;
AccessionQ8CJG0AG02_MOUSE;
ProducedinRabbit
ApplicationsWesternBlotting(WB),Immunochemistry(IHC)andImmunoprecipitation(IP).TherecommendedconcentrationforIHCinformalinfixedandparaffinembeddedtissuesandformalin/acetonefixedtissuesis1:200-1:500.ForWB,therecommendedconcentrationis1:1,000to1:2,000.TheelFC2proteinhasapredictedlengthof860residuesandtheMWofthemonomeris94kDa.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificitySpecificityhasbeenconfirmedbyIHC,WBandIPinmousebrain.ThisantibodyisexpectedtorecogniseatleastelF2c-1,2and3sincetheyhaveidenticalC-termini.
Cross-reactivityHuman;mouse;rat;TheAgoproteinsarehighlyconservedsocross-reactivitywithotherspeciesisexpected.
BlastURLClickhere
FormLyophilisedfromPBS
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAtleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlityandat4°Cwithanappropriateantibacterialagent.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase
SpecificReferencesHuangKL,ChadeeAB,ChenCY,ZhangY,ShyuAB.(2013)"PhosphorylationatintrinsicallydisorderedregionsofPAM2motif-containingproteinsmodulatestheirinteractionswithPABPC1andinfluencesmRNAfate."RNA.2013Jan22.[Epubaheadofprint].
LugliG.etal(2008)ExpressionofmicroRNAsandtheirprecursorsinsynapticfractionsofadultmouseforebrain.JNeuRochem.Jul;106(2):650-61.
LugliG.etal(2005)DicerandeIF2careenrichedatpostsynapticdensitiesinadultmousebrainandaremodifiedbyneuronalactivityinacalpain-dependentmanner.JNeurochem.Aug;94(4):896-905.
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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