产品编号：R-1721-100
市 场 价：¥6540.00
场 地：美国(厂家直采)
联系QQ：1570468124
电话号码：4000-520-616
邮 箱：
info@ebiomall.com
商品介绍
| Description | TheproteinidentifiedasCD44isalsoknownasthereceptorforhyaluronicacid(HA).Theproteinmediatescell-cellandcell-matrixinteractionsthroughitsaffinityforHA,andpossIBLyalsothroughitsaffinityforotherligandssuchasosteopontin,collagens,andmatrixmetalloproteinases(MMPs).AdhesionwithHAplaysanimportantroleincellmigration,tumorgrowthandprogression.Incancercells,CD44mayplayanimportantroleininvadopodiaformation,anditalsoisinvolvedinlymphocyteactivation,recirculationandhoming,andinhematopoiesis.AlteredexpressionordysfunctionofCD44causesnumerouspathogenicphenotypes.CD44hasgreatproteinheterogeneityduetonumerousalternativesplicingandpost-translationalmodificationevents.Biosensis"anti-CD44rabbitpolyclonalantibodyisanewantibodymadeagainstasyntheticpeptideepitopeneartheveryC-terminus,cytoplasmicdomainofhumanCD44.Theantibodyhasbeenshowntoreactwithmultiplespeciesincludinghuman,mouseandrat,inbothwesternblotandimmunohistochemistryapplicationsincludingformalinfixed,paraffinembeddedtissues.Seeapplicationsdetailforspecificuseinstructions. |
| BatchNo. | seeviallabel |
| Unitsize | 100µg |
| Antigen | AsyntheticpeptidecorrespondingtoasequenceattheC-terminusofhumanCD44cytoplasmicdomainaa728-742.Theimmunogendiffersbyonlysingleaminoacidbetweenhuman,mouseandratproteins. |
| Sequence | DETRNLQNVDMKIGV |
| AntigenLocation | cytoplasmic,C-terminus |
| AntigenLength | 15aa |
| AntibodyType | polyclonal |
| Isotype | IgG |
| OtherNames | CDw44,Epican,ExtracellularmatrixreceptorIII,ECMR-III,GP90lymphocytehoming/adhesionreceptor,HUTCH-I,Heparansulfateproteoglycan,Hermesantigen,Hyaluronatereceptor,Phagocyticglycoprotein1,PGP-1,PhagocyticglycoproteinI,PGP-I,CD_antigen:CD44 |
| Accession | P16070 |
| Producedin | Rabbit |
| MolecularWeight | Variabledependinguponsplicing,80-to250-kDa |
| Purity | Affinitypurifiedoverpeptide |
| Applications | WB:Westernblot:reducedRIPAsamplesormembranepreparations(0.1-.5ug/mL)dependentuponantigenloadandantibodyincubationtimesanddetectionsubstrateused. IH:frozenoracetonefixedtissue:0.5-1.0ug.mL,permeABIlizationisnecessaryasepitopeisinternal IH(P):1-2ug/mLwithHEIRtreatmentrequired. |
| Form | lyophilized. |
| Appearance | Eachvialcontains100ugpurifiedantibody,and5mgBSA,0.9mgNaCl,0.2mgNa2HPO4,0.05mgThimerosal,0.05mgNaN3. |
| Reconstitution | 0.2mlofdistilledwaterwillyieldaconcentrationof500μg/ml. |
| Storage | At-20˚Cforoneyear.Afterreconstitution,at4˚Cforonemonth.Itcanalsobedividedintoaliquotsandstoredfrozenat-80˚Cforalongertime.Avoidrepeatedfreezingandthawing. |
| ExpiryDate | 12monthsafterpurchase. |
品牌介绍
Biosensis专注于神经科学领域的抗体和试剂的开发，特别是神经营养因子和神经营养因子受体。 近30年来，Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子，我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症（AD）、帕金森氏症（PD）和肌萎缩侧索硬化（ALS）疾病，以及自噬和代谢应激障碍，包括肥胖、代谢综合征的研究、神经免疫学和炎症。
公司介绍
产品分类
TR-200-BG
PE-1243-50
Antibody Kits
PE-1246-5
TR-100-BG
S-1754-500
Neurotrophic Factors
Diabetes & Obesity
Intracellular Trafficking
PE-1239-5
Neuropeptides & Receptors
B-100-PS
Receptors & Channel Molecules
2 Plate ELISA kits
M-1763-100-FT
TR-200-BGT
PE-1239-2
PE-1242-5
M-1249-100
Neurotrophic Factor Receptors
Cell Cycle Regulators
S-1759-100
PE-1606-100
PE-1762-100
B-200-PS
PE-019-100
PE-1241-5
PE-003-100
1 Plate ELISA kits
BL-003-1000
PE-1246-2
Sensory Nervous System
PE-1253-100
TR-100-FJ
BL-005-500
Neuroendocrine
M-1728-100
DNA Damage & Repair
PE-001-100
PE-1608-1
TR-400-AG
PE-1243-25
Cell Markers
PE-1608-5
TR-100-FJT
Autophagy
PE-1242-2
Other Neuronal
Neurotransmitters & Enzymes
Antioxidant Enzymes
Neuronal Markers
Tag Antibodies
BL-004-500
PE-019-25
PE-1608-10
BL-002-1250
Receptor Body Chimeras
Signalling & Transcription
Matrix & Adhesion Molecules
BL-001-1250
Cancer
PE-019-500
Stem Cells
Junction Proteins
TR-300-AG
Apoptosis
PE-1252-100
Growth Factors
Development
Alzheimer\'s / Parkinson\'s
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