Description | ThisreceptorforUrokinasePlasminogenActivatorhasaroleinlocalizingandpromotingplasminformation.Atleast3isoformsareproducedbyalternativesplicing(Ref:SWISSPROT). |
BatchNo. | Seeproductlabel |
Unitsize | 100µg |
Antigen | Asyntheticpeptidecorrespondingtoaregion(293-304aa)fromhumanUrokinaseplasminogenactivatorsurfacereceptor(UPAR). |
AntigenLocation | 293-304 |
OtherNames | MonocyteactivationantigenMo3;CD87;U-PAR;PLAUR;uPAReceptor; |
Accession | Q03405UPAR_HUMAN; |
Producedin | Rabbit |
Applications | WesternBlotting(WB)andImmunohistochemistry(IHC).Aconcentrationof0.1-0.5µg/mlisrecommendedforWB.HumanUPAR(isoform1precursor)hasapredictedlengthof335aminoacidsandMWof37kDa.Aconcentrationof0.5-2.0µg/mlisrecommendedforIHCtodetecttheproteininformalinfixedandparaffinembeddedtissues.Heatmediatedantigenretrievalisrequired.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | ThespecificityofthisantibodyhasbeenconfirmedbyWBandIHCagainsttheantigen. |
AntibodyAgainst | Urokinaseplasminogenactivatorsurfacereceptor |
Cross-reactivity | Human; |
Blastit | Ifyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenproteins.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample. |
BlastURL | Clickhere |
Form | Lyophilisedwith5mgBSA,0.9mgNaCl,0.2mgNa2HPO4,0.05mgThimerosal,0.05mgNaN3 |
Appearance | Whitepowder |
Reconstitution | Reconstitutein100µlofsteriledistilledwatertoachieveanantibodyconcentrationof1mg/ml.Centrifugetoremoveanyinsolublematerial. |
Storage | Atleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles. |
ExpiryDate | 12monthsafterpurchase |
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