Biosensis/Rabbit polyclonal antibody to human Tumor necrosis factor receptor 1 (195-211): Affinity purified/R-1127-100/100 µg,Biosensis,,Biosensis,Biosensis inc,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Biosensis/Rabbit polyclonal antibody to human Tumor necrosis factor receptor 1 (195-211): Affinity purified/R-1127-100/100 µg

产品编号：R-1127-100

市场价：¥6540.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$327.00

品牌： Biosensis

公司：Biosensis

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商品介绍

Description	Tumor necrosis factor receptor 1 (TNF Receptor 1) binds cytokines TNF-alpha and TNF-beta resulting in the activation of pathways involved in both cell survival and apoptosis. TNF Receptor 1 contains an extracellular death domain that binds to the death domain adaptor protein TRADD and triggers the activation of caspases. At least 3 isoforms are produced by alternative splicing.
Batch No.	See product label
Unit size	100 µg
Antigen	A synthetic peptide corresponding to a region (195-211) from human Tumor necrosis factor receptor 1 (precursor). To enhance the immunological response, this peptide was coupled to carrier protein BSA.
Other Names	p60; TNF-R1; TNF-RI; TNFR-I; p55; CD120a; TNFRSF1A; TNFAR; TNFR1;
Accession	P19438 TNR1A_HUMAN;
Produced in	Rabbit
Purity	Affinity purified on antigen column
Applications	Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0 µg/ml is recommended for WB. Human TNF Receptor 1 (precursor) has a predicted length of 455 residues and MW of 51 kDa. A concentration of 1.0 µg/ml is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Specificity	The specificity of this antibody has been confirmed by WB and IHC against the antigen.
Cross-reactivity	Human;
Blast it	If you wish to use this product in a species other than those specified here and want to determine the amino acid sequence homology between the immunogen and the corresponding protein in that species, simply copy the amino acid sequence for this immunogen and test it on the BLAST database that you can access through the link below. Please note that antibodies raised against synthetic peptides are quite often very specific for that peptide. What this means in practise is that a single amino acid difference may be enough to restrict the specificity to a particular molecule. The BLAST database can also be used to compare any amino acid sequence between species and between protein. The full amino acid sequence of the target protein can be found by following the link in the Accession field. You can then search any amino acid sequence in the target protein using the BLAST database. When selecting a sequence to search, please choose carefully, as the sequence you choose may be a precursor rather than the mature protein for example.
Form	Lyophilised with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
Reconstitution	Reconstitute in 100 µl of sterile distilled water to achieve an antibody concentration of 1 mg/ml. Centrifuge to remove any insoluble material.
Storage	At least 12 months after purchase at 2 - 4°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles
Expiry Date	12 months after purchase

品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发，特别是神经营养因子和神经营养因子受体。 近30年来，Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子，我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症（AD）、帕金森氏症（PD）和肌萎缩侧索硬化（ALS）疾病，以及自噬和代谢应激障碍，包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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