商品介绍
| Description | Humanbeta-Lipotropinisa93aminoacidpolypeptidethatiscleavedfromcarboxy-terminalfragmentoftheprecursorpro-opiomelanocortin(POMC).Itstimulatesmelanocytestoproducemelanin,andcanalsobecleavedintosmallerpeptidesincludingopioidpeptides:gamma-lipotropin,alpha-MSH,beta-MSH,gamma-MSH,alpha-endorphin,beta-endorphin,gamma-endorphinandmet-enkephalin |
| BatchNo. | Seeproductlabel |
| Unitsize | 50µg |
| Antigen | Syntheticpeptide(179-267aa)ofhumanbeta-Lipotropinconjugatedtothyroglobulinwasusedastheimmunogen. |
| Sequence | 179-267 |
| OtherNames | Beta-LPH;Lipotropinbeta;Pro-opiomelanocortin;POMC; |
| Accession | P01189COLI_HUMAN;P01190COLI_BOVIN; |
| Producedin | Rabbit |
| Applications | Adilutionof5-10µg/mlisrecommendedforimmunohistochemistryusingformalinfixedandparaffinembeddedtissuesandfor4%paraformaldehydefixedfrozentissues.Adilutionof5-15µg/mlisrecommendedforimmunofluorescence.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
| SpeciesAgainst | Human |
| AntibodyAgainst | betaLipotropin |
| Cross-reactivity | Human;mouse;rat.Beta-Lipotropinishighlyconservedsocross-reactivitywithotherspeciesisexpected.Cross-reactivitywithotheropioidpeptidesisasfollows:withLeu-enkephalin0.01%;withMet-Enkephalin0.01%;withbeta-endorphin0.01% |
| Blastit | Ifyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenproteins.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample. |
| BlastURL | Clickhere |
| Form | LyophilisedwithBSA |
| Appearance | Whitepowder |
| Reconstitution | Reconstitutein0.05mlofPBS(pH7.4).Centrifugetoremoveanyinsolublematerial. |
| Storage | Atleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlityandat4°Cwithanappropriateantibacterialagent.Avoidfreeze-thawcycles |
| ExpiryDate | 12monthsafterpurchase |
品牌介绍
Biosensis专注于神经科学领域的抗体和试剂的开发，特别是神经营养因子和神经营养因子受体。 近30年来，Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子，我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症（AD）、帕金森氏症（PD）和肌萎缩侧索硬化（ALS）疾病，以及自噬和代谢应激障碍，包括肥胖、代谢综合征的研究、神经免疫学和炎症。
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