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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Mouse monoclonal antibody to proNGF (30-41), [Clone BS312] - Biotinylated/M-1778-50-B/50 µg
产品编号:M-1778-50-B
市  场 价:¥5940.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$297.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Mouse monoclonal antibody to proNGF (30-41), [Clone BS312] - Biotinylated/M-1778-50-B/50 µg
商品介绍
DescriptionNervegrowthfactor(NGF)issynthesizedasaprecursor(proNGF)whichmaybereleasedandhavephysiologicalfunctionstocausecelldeath.Itbindsneurotrophinreceptorp75andsortilinandmayalsobeimportantforthedevelopmentofnervoussystem.proNGFissynthesizedintargettissuesandglia,transportedretrogradelyandmaybereleased.

BiosensisnowoffersbiotinylatedproNGFantibodyallowingmoreflexibilityinexperimentaldesignbyusingthebiotin-avidin/streptavidindetectionmethod.TheABIlityofbiotinylatedproNGFantibodytodetectproNGFhasbeenvalidatedbyWB.
RelatedproductsPurified,non-biotinylatedproNGFantibody,cat#M-1738-100
BatchNo.Seeproductlabel
Unitsize50µg
AntigenAsyntheticpeptide(C-HTIPQAHWTKLQ,aa:30-41)ofhumanproNGFproteinhasbeenusedastheimmunogen.Thesequenceislocatedonthepro-domainoftheproNGFfull-lengthproteinandis80%homologoustomouseandratproNGF.
AntibodyTypeMousemonoclonalIgGantibody
IsotypeIgG2b,lamBDa-lightchain
CloneBS312
OtherNamesPro-brainnervegrowthfactor;proNGF;NGF
AccessionNGF_HUMAN
ProducedinMouse
PurityAntibodywaspurifiedfromcellculturesupernatantbyProteinGchromatography,biotinylatedandbuffer-exchangedintoPBS,pH7.4buffer
ApplicationsThebiotinylatedproNGFantibodyhasbeentestedbyWesternBlotting(0.1-0.5µg/mL)andisalsoexpectedtoworkinapplicationsvalidatedfortheunlabelledantibody(M-1738-100)atsameorhigherdilutions:FlowCytometryandImmunofluorescence.

Otherapplicationsnotyettested.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityHuman
Cross-reactivitySpeciescross-reactivitynottested.
ConjugateBiotin
FormLyophilisedfromasolutioncontainingPBSbufferpH7.4with3%trehalose,withoutpreservatives.
ReconstitutionSpinvialbrieflybeforeopening.Reconstitutein50µLofsterile,ultrapurewatertogiveaconcentrationof1mg/mL.Centrifugetoremoveanyinsolublematerial.Finalbuffercontainsnopreservative.
StorageAfterreconstitutiondivideintoaliquotsandstoreat-20ºCforahigherstability.Antibodycontainsnopreservatives.Storeat4ºCwithanappropriateantibacterialagent.Usesterilemethods.HighestpurityGlycerol(1:1)maybeaddedforanadditionalstabilitywhenstoredatrefrigeratedorfreezingtemperatures.Avoidrepetitivefreeze/thawcycles.
ExpiryDate12monthsafterpurchaseifunopened
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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