Description | CollagenIVisamajorconstituentoftheglomerularbasementmembranes.Itisaheterotrimericproteincomposedof3alphasubunitsencodedby6differentgenes;alpha1(IV)throughalpha6(IV). |
BatchNo. | Seeproductlabel |
Unitsize | 100µg |
Antigen | HumanCollagenTypeIV |
Clone | Col-30 |
OtherNames | Collagenalpha-1(IV)chain;Arresten;COL4A1;COL4A2;COL4A3;COL4A4;COL4A5;Tumstatin;Goodpastureantigen; |
Accession | P02462CO4A1_HUMAN; |
Producedin | Mouse |
Purity | IgG |
Applications | Immunohistochemistry(IHC).Aconcentrationof0.5-1.0µg/mlisrecommendedtodetectCollagenIVinformalinfixedandparaffinembeddedtissuesaswellasformalin/acetonefixedfrozentissues.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | ThespecificityofthisantibodyhasbeenconfirmedbyIHCagainsttheantigen. |
Cross-reactivity | Human |
Blastit | Ifyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample. |
Form | Liquid(0.5ml).50%glycerol,0.9mgNaCland0.2mgNa2HPO4 |
Reconstitution | TheliquidformulationshouldbedilutedinPBS(pH7.4) |
Storage | Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles. |
ExpiryDate | 12monthsafterpurchase |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。