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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Rabbit antibody to MAP1LC3 C : whole serum/R-140-100/100 µl
产品编号:R-140-100
市  场 价:¥5940.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$297.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Rabbit antibody to MAP1LC3 C : whole serum/R-140-100/100 µl
商品介绍
DescriptionFUNCTION:Probablyinvolvedinformationofautophagosomalvacuoles(autophagosomes).SUBUNIT:3differentlightchains,LC1,LC2andLC3,canassociatewithMAP1AandMAP1Bproteins.SUBCELLULARLOCATION:LC3-I:Cytoplasm.LC3-II:Intracytoplasmicmembrane;lipid-anchor.LC3-IIbindstotheautophagicmembranes.TISSUESPECIFICITY:Mostabundantinplacenta,lungandovary.PTM:TheprecursormoleculeiscleavedbyAPG4B/ATG4Btoformthecytosolicform,LC3-I.ThisisactivatedbyAPG7L/ATG7,transferredtoATG3andconjugatedtophospholipidtoformthemembrane-boundform,LC3-II.SIMILARITY:BelongstotheMAP1LC3family.
BatchNo.Seeproductlabel
Unitsize100µl
AntigenAsyntheticpeptide(CQEEVAGIRAKF)correspondingtotheN-terminalofhumanMAP1LC3CconjugatedtoBlueCarrierProteinhasbeenusedastheimmunogen.ThepeptideishomologouswiththecorrespondingsequencederivenfromMAP1LC3CproteininMacacamulatta(monkey)andCanisfamiliaris(dog).
OtherNamesMicrotubule-associatedproteins1A/1Blightchain3C;Microtubule-associatedprotein1lightchain3gamma;MAP1A/MAP1BLC3C;MAP1A/1Blightchain3C;MAP1lightchain3-likeprotein3;Autophagy-relatedproteinLC3C;Autophagy-relatedubiquitin-likemodifierLC3C;APG8c;MAP1LC3C
AccessionMLP3C_HUMAN
ProducedinRabbit
PurityWholeserum
ApplicationsIHC,immunofluorescence,WB.Adilutionof1:100to1:1000dilutionisrecommendedfortheseapplications.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityIHCandWBconfirmedthespecificityforMAP1LC3C.ThisantibodyshouldrecogniseMAP1LC3ConlyandnottheotherformsMAP1LC3AandMAP1LC3B.
Cross-reactivityHuman,otherspecieshavenotyetbeentested.
FormLyophilised
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforanadditionalstability.Avoidrepetitivefreeze/thawcycles.
ExpiryDate12monthsafterpurchase
References1.GreenbergJT.DevCell.8(6):799-801.(2005)
2.BaehreckeEH.NatRevMolCellBiol.6(6):505-10.(2005)
3.LevineB.Cell.120(2):159-62.(2005)
4.TanidaI.,etal.J.Biol.Chem.279:36268-36276(2004)
5.LumJJ,etal.NatRevMolCellBiol.6(6):439-48.(2005)
6.TanidaI.,etal.Int.J.Biochem.CellBiol.36:2503-2518(2004)
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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