Description | FUNCTION:Involvedinintra-Golgitraffic.Modulatesintra-GolgitransportthroughcouplingbetweenNSFactivityandSNAREsactivation.ItfirststimulatestheATPaseactivityofNSFwhichinturnstimulatestheassociationwithGOSR1.SUBUNIT:Monomer.InteractswithGABRG2,NSF,GOSR1andbeta-tubulin.InteractswithULK1.SUBCELLULARLOCATION:Golgiapparatus.TISSUESPECIFICITY:Ubiquitous.Expressedathighlevelsinthebrain,heart,prostate,ovary,spleenandskeletalmuscle.Expressedatverylowlevelsinlung,thymusandsmallintestine.SIMILARITY:BelongstotheMAP1LC3family.ESTIMATEDMOLECULARWEIGHT:13.667kDa. |
BatchNo. | Seeproductlabel |
Unitsize | 100µl |
Antigen | Asyntheticpeptide(CVESAKIRAKYP)correspondingtotheN-terminalofhumanGABARAPL2(GABARAPL2)proteinhasbeenusedastheimmunogen.ThesequenceishomologouswithmouseandratformofGABARAPL2(GABARAPL2). |
OtherNames | Gamma-aminobutyricacidreceptor-associatedprotein-like2;GABA(A)receptor-associatedprotein-like2;Gangliosideexpressionfactor2;GEF-2;Generalproteintransportfactorp16;MAP1lightchain3-relatedprotein;GABARAPL2;FLC3A;GEF2; |
Accession | GBRL2_HUMAN GBRL2_MOUSE GBRL2_RAT |
Producedin | Rabbit |
Purity | Wholeserum |
Applications | IHC,immunofluorescence,WB.Adilutionof1:200to1:1000dilutionisrecommendedfortheseapplications.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | IHC,WBandELISAconfirmedthespecificityforGABARAPL2(GABARAPL2).A14kDaband,thatcorrespondstothemolecularweightofGABARAPL2,isdetectedviawesternblotanalysis. |
Cross-reactivity | Human,rat.Otherspeciesnotyettested. |
Form | Lyophilised |
Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Afterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforanadditionalstability.Avoidrepetitivefreeze/thawcycles. |
ExpiryDate | Sixmonthsafterpurchase |
References | 1.OkazakiN.etal.BrainRes.Mol.BrainRes.85:1-12(2000) 2.XinY.etal.Genomics74:408-413(2001) 3.TheMGCProjectTeam.GenomeRes.14:2121-2127(2004) |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。