Description | Beclin-1playsacentralroleinautophagy.Itmayalsoplayaroleinantiviralhostdefense.Itisubiquitouslyexpressedanditlocalisestothecytoplasm,golgiapparatusmembrane,andindendritesandcellbodiesofcerbellarPurkinjecells.Theunprocessedprecursorhasalengthof450aminoacidsandanestimatedmolecularweightof51.89kDa. |
BatchNo. | Seeproductlabel |
Unitsize | 100µl |
Antigen | C-terminalofhumanBeclin-1conjugatedtoBlueCarrierProtein. |
OtherNames | Coiled-coilmyosin-likeBCL2-interactingprotein;ProteinGT197;APG6;BECN1; |
Accession | BCN1_HUMAN |
Producedin | Rabbit |
Purity | Wholeserum |
Applications | IHC.Adilutionof1:100to1:2000dilutionisrecommendedfortheseapplications.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | SpecificforBeclin-1. |
Cross-reactivity | Human,otherspecieshavenotyetbeentested. |
Form | Lyophilised |
Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Afterreconstitutionkeepaliquotsat-20°CforahigherstABIlity,andat4°Cwithanappropriateantibacterialagent.Avoidrepetitivefreeze/thawcycles. |
ExpiryDate | Sixmonthsafterpurchase |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。