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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Rabbit antibody to ATG9A (APG9L1): whole serum/R-160-100/100 µl
产品编号:R-160-100
市  场 价:¥5940.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$297.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Rabbit antibody to ATG9A (APG9L1): whole serum/R-160-100/100 µl
商品介绍
DescriptionFUNCTION:Playsaroleinautophagy.SUBCELLULARLOCATION:Membrane;multi-passmembraneprotein(Potential).ALTERNATIVEPRODUCTS:3namedisoformsproducedbyalternativesplicing.SIMILARITY:BelongstotheATG9family.INYEAST:FUNCTION:Involvedinautophagyandcytoplasmtovacuoletransport(Cvt)vesicleformation.RecruitesATG23andATG8tothepre-autophagosomalstructure.SUBUNIT:InteractswithATG18,ATG2andATG23.SUBCELLULARLOCATION:Membrane;multi-passmembraneprotein.Preautophagosomalstructure;preautophagosomalstructuremembrane;multi-passmembraneprotein.Note=Pre-autophagosomalandotherperivacuolarpunctatestructures.ThepropertraffickingofATG9betweenthepre-autophagosomalstructureandtheotherpunctatestructuresrequiresATG2,ATG18,ATG23,theATG1-ATG13complexandthephosphatidylinositol3-kinasecomplexI.SIMILARITY:BelongstotheATG9family.
BatchNo.Seeproductlabel
Unitsize100µl
AntigenAsyntheticpeptide(CWHRRESDESGE)correspondingtotheC-terminalofhumanAPG9A(APG9L1)proteinhasbeenusedastheimmunogen.ThepeptideishomologouswiththecorrespondingsequencederivedfromAPG9A(APG9L1)proteininmouse,rat,S.cerevisiae,Macacamulatta(monkey)andCanisfamiliaris(dog).
OtherNamesAutophagy-relatedprotein9A;APG9-like1;Autophagy-relatedprotein9;APG9A;ATG9A;APG9L1
AccessionATG9L1_HUMAN
ATG9L1_MOUSE
ATG9L1_RAT
ATG9L1_Saccharomycescerevisiae
ATG9L1_Macacamulatta
ATG9L1_Canisfamiliaris
ProducedinRabbit
PurityWholeserum
ApplicationsIHC,immunofluorescence,WB.Adilutionof1:100to1:3000dilutionisrecommendedfortheseapplications.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityIHC,WBandELISAconfirmedthespecificityforATG9A(APG9L1).
Cross-reactivityHuman,rat.Otherspeciesnotyettested.
FormLyophilised
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforanadditionalstability.Avoidrepetitivefreeze/thawcycles.
ExpiryDateSixmonthsafterpurchase
SpecificReferences1.ParkYEetal(2009)Autophagicdegradationofnuclearcomponentsinmammaliancells.Autophagy.2009Aug;5(6):795-804.
References1.OtaT,eal.Nat.Genet.36:40-45(2004).
2.DelaveauT.T.D,etal.Yeast12:1587-1592(1996).
3.JacqC,etal.Nature387:75-78(1997).
4.TsukadaM.,OhsumiY.FEBSLett.333:169-174(1993).
5.HardingT.M,etal.J.CellBiol.131:591-602(1995).
6.HardingT.M,etal.J.Biol.Chem.271:17621-17624(1996).
7.LangT,etal.J.Bacteriol.182:2125-2133(2000).
8.NodaT,etal.J.CellBiol.148:465-480(2000).
9.KimH,etal.Proc.Natl.Acad.Sci.U.S.A.103:11142-11147(2006).
10.TuckerK.A,etal.J.Biol.Chem.278:48445-48452(2003).
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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