Description | FUNCTION:Requiredforautophagy.SUBUNIT:ConjugatedtoATG5.SUBCELLULARLOCATION:Cytoplasm.ALTERNATIVEPRODUCTS:2namedisoformsproducedbyalternativesplicing.TISSUESPECIFICITY:Ubiquitous.SIMILARITY:BelongstotheATG12family. |
BatchNo. | Seeproductlabel |
Unitsize | 100µl |
Antigen | AsyntheticpeptidecorrespondingtotheN-terminalofhumanATG12proteinhasbeenusedastheimmunogen.Noimmunogeniccarrierproteinwasconjugatedtotheimmunogen.Instead,AdjukineB(seetheAdjuvantsinBiosensis"productlist)hasbeenusedtoorchestrate/boosttheimmuneresponse. |
OtherNames | Autophagy-relatedprotein12;APG12-like;APG12;ATG12;APG12;APG12L |
Accession | ATG12_HUMAN |
Producedin | Rabbit |
Purity | Wholeserum |
Applications | IHC,immunofluorescence,WB.Adilutionof1:200to1:1000dilutionisrecommendedfortheseapplications.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | IHCandWBconfirmedthespecificityforATG12. |
Cross-reactivity | Human,rat |
Form | Lyophilised |
Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Afterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforanadditionalstability.Avoidrepetitivefreeze/thawcycles. |
ExpiryDate | Sixmonthsafterpurchase |
References | 1.Mizushima,N.etal.J.Biol.Chem.273(51):33889-33892(1998). 2.Tanida,I.etal.Biochem.Biophys.Res.Commun.296(5):1164-1170(2002). 3.Tanida,I.etal.J.Biol.Chem.277(16):13739-13744(2002). |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。