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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Sheep antibody to Peroxiredoxin-6 (NSGPx): whole serum/S-073-100/100 µl
产品编号:S-073-100
市  场 价:¥5940.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$297.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Sheep antibody to Peroxiredoxin-6 (NSGPx): whole serum/S-073-100/100 µl
商品介绍
DescriptionFUNCTION:Involvedinredoxregulationofthecell.Canreducehydrogenperoxideandshortchainorganic,fattyacid,andphospholipidhydroperoxides.Mayplayaroleintheregulationofphospholipidturnoveraswellasinprotectionagainstoxidativeinjury.SUBUNIT:Homotetramer.MayinteractwithHTR2A.SUBCELLULARLOCATION:Cytoplasm.Lysosome.Alsofoundinlungsecretoryorganelles.MISCELLANEOUS:Theactivesiteistheredox-activeCys-47oxidizedtoCys-SOH.Cys-SOHmayrapidlyreactwithaCys-SHoftheothersubunittoformanintermoleculardisulfidewithaconcomitanthomodimerformation.Theenzymemaybesubsequentlyregeneratedbyreductionofthedisulfidebythioredoxin.MISCELLANEOUS:IrreversIBLyinactivatedbyoveroxidationofCys-47(toCys-SO(3)H)uponoxidativestress.SIMILARITY:BelongstotheahpC/TSAfamily.Rehydrinsubfamily.
BatchNo.Seeproductlabel
Unitsize100µl
AntigenRatrecombinantPeroxiredoxin-6
OtherNamesNon-seleniumglutathioneperoxidase;antioxidantprotein2;1-Cysperoxiredoxin;1-CysPRX;Acidiccalcium-independentphospholipaseA2;NSGPx;Thiol-specificantioxidantprotein;Prdx6;Aipla2;Aop2;Tsa
AccessionPRDX6_RAT
PRDX6_HUMAN
PRDX6_MOUSE
ProducedinSheep
PurityWholeserum
ApplicationsIHC,WB,ELISA.ThisantibodyworkssuperblyinImmunohistochemistryonfrozenorparaffinembeddedtissues.Antigenretrievalhasbeenusedintestingbutmaynotbenecessary.Typicalworkingdilutionsforroutineimmunohistochemistryare1:100to1:1000dependingontissueanddetectionmethod.Forwesternblottingadilutionrangeof1:500to1:2000isrecommended.Adilutionof1:1000to1:2000isrecommendedforELISA.Thisantiserumstainsthecytoplasmofepithelialcellsintheratandmouselungandratandhumanbrainastrocytes.ItstainshumanbrainastrocytesinParkinson'sandAlzheimer'sdiseaseandthecentralcoreofsomeLewybodiesinParkinson'sdiseaseanddementiawithLewybodies.Othertissueshavenotyetbeentested.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThisantibodyhasbeenshowntobespecificforPeroxiredoxin-6protein.
Cross-reactivityRat,humanandmouse,otherspecieshavenotyetbeentested.
BlastitIfyouwouldliketousethisproductinanotherspeicesotherthanthosespecifiedhere,ortoseethesharedidentitybetweentheimmunogenusedhereindifferentspeicesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis.
FormLyophilised
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Avoidrepetitivefreeze/thawcycles.Glycerol(1:1)maybeaddedforanadditionalstability.
ExpiryDate12monthsafterpurchase
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品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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