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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Rabbit polyclonal antibody to glutathione peroxidase 1 (GPx-1) [175-194]: whole serum/R-1588-100/100 µl
产品编号:R-1588-100
市  场 价:¥5940.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$297.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Rabbit polyclonal antibody to glutathione peroxidase 1 (GPx-1) [175-194]: whole serum/R-1588-100/100 µl
商品介绍
DescriptionGlutathioneperoxidase1hasaroleindetoxificationofhydrogenperoxideandisoneofthemostimportantantioxidantenzymesinhumans.Itexistsasahomotetramerwhichlocalisestothecytoplasm.Itbelongstotheglutathioneperoxidasefamily.Glutathioneperoxidase1isoneoffewproteinsinhighervertebratestocontainselenocysteine,whichoccursattheactivesiteofglutathioneperoxidaseandiscodedbyUGA,thatnormallyfunctionsasatranslationterminationcodon.ThisproteinhasapolyalaninesequencepolymorphismintheN-terminalregion,whichincludesthreealleleswithfive,sixorsevenalaninerepeats.Theallelewithfivealaninerepeatsissignificantlyassociatedwithbreastcancerrisk.Atleasttwoalternativelysplicedisoformshavebeenidentified.
BatchNo.Seeproductlabel
Unitsize100µl
AntigenAsyntheticpeptide(RRYSRRFQTIDIEPDIEALL)correspondingtotheaminoacids175-194ofhumanglutathioneperoxidase1(GPx-1)conjugatedtodiphtheriatoxinhasbeenusedastheimmunogen.
AntibodyTypePolyclonal
OtherNamesGlutathioneperoxidase1;GPx-1;GSHPx-1;Cellularglutathioneperoxidase;GPX1;
AccessionP07203GPX1_HUMAN;
ProducedinRabbit
ApplicationsIHC,WBandELISA.ThisantibodyworkssuperblyinIHConfrozenorwaxembeddedtissues.Antigenretrievalhasbeenusedintestingbutmaynotbenecessary.TypicalworkingdilutionsforroutineIHCare1:200to1:1,000dependingontissueanddetectionmethod.ForWBadilutionrangeof1:1,000to1:4,000isrecommended.ForELISA,adilutionof1:1,000to1:4,000isrecommended.Thisantiserumhasextremelyhightitre,itstainshumanandratglialcellsintenselyandtosomeextentalsostainsneurons.Othertissueshavenotyetbeentested.OnWBunderreducingconditionsrecognisesa22kDproteininhumanbraintissueandSigmaglutathioneperoxidase(G-4013)isolatedfromhumanerythrocytes.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityHumanandratcellularseleniumdependentglutathioneperoxidase.
Cross-reactivityHuman;rat;
BlastURLClickhere
FormLyophilizedserumwith0.02%thimerosal
ReconstitutionReconstituteinsteriledistilledwater.Centrifugetoremoveanyinsolublematerial.
StorageAtleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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