Description | GPx-PbelongstotheglutathioneperoxidasefamilywhichareresponsIBLeforthedetoxificationofhydrogenperoxide.Itprotectscellsandenzymesfromoxidativedamage,bycatalyzingthereductionofhydrogenperoxide,lipidperoxidesandorganichydroperoxide,byglutathione.GPx-Pissecretedinplasmaandexistsasahomotetramer. |
BatchNo. | Seeproductlabel |
Unitsize | 100µl |
Antigen | Asyntheticpeptide(FEKGDVNGEKEQKFYTFLKN)correspondingtotheaminoacids135-154ofhumanglutathioneperoxidase3(GPx-P)conjugatedtodiphtheriatoxinhasbeenusedastheimmunogen.Thepeptideishomologouswiththecorrespondingsequencederivedfromglutathioneperoxidase3(GPx-P)proteininmouse,rat,orangutanandbovine. |
OtherNames | Extracellularglutathioneperoxidase;GPx-P;GSHPx-3;GPx-3;Plasmaglutathioneperoxidase;GSHPx-P;GPX3;GPXP |
Accession | GPX3_HUMAN |
Producedin | Rabbit |
Purity | Wholeserum |
Applications | IHC,only.Adilutionof1:1000to1:5000isrecommendedforimmunohistochemistrydependingondetectionmethodbutenduserwillneedtodeterminedilutiontosuitapplication.Antigenretrievalisrecommended.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | Thisantibodyhasbeenshowntobespecificforglutathioneperoxidase3protein(GPx-P)throughstainingandblockingstudies. |
Cross-reactivity | Humanandrat,otherspecieshavenotyetbeenested. |
Blastit | Ifyouwouldliketousethisproductinanotherspeciesotherthanthosespecifiedhere,ortoseethesharedidentitybetweentheimmunogenusedhereindifferentspeciesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis. |
Form | Lyophilised |
Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Afterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Avoidrepetitivefreeze/thawcycles. |
ExpiryDate | 12monthsafterpurchase |
References | 1.TakahashiK,etal.J.Biochem.108:145-148(1990). 2.ChuF.-F,etal.Blood79:3233-3238(1992). |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。