Description | SOD1bindscopperandzincionsansisoneoftwoisozymesresponsIBLefordestroyingfreesuperoxiderADIcalswhicharenormallyproducedwithinthecellsandwhicharetoxictoBIOLOGicalsystems.SOD1isasolublecytoplasmicprotein,actingasahomodimertoconvertsuperoxideradicalstomolecularoxygenandhydrogenperoxide.DefectsinSOD1arethecauseofamyotrophiclateralsclerosistype1(ALS1)whichisaneurodegenerativedisorderaffectingupperandlowermotorneuronsandresultinginfatalparalysis. |
Unitsize | 100µg |
Antigen | Afulllengthrecombinanthumansuperoxidedismutase(SOD1)proteinwithaGSTtaghasbeenusedastheimmunogen. |
Isotype | IgG2aKappa |
Clone | 10D5 |
OtherNames | Superoxidedismutase[Cu-Zn];Superoxidedismutase1;hSod1;SOD1; |
Accession | P00441SODC_HUMAN; |
Producedin | Mouse |
Applications | WB,ELISA.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Cross-reactivity | Human; |
BlastURL | Clickhere |
Form | Liquid.1xPBS,pH7.2 |
Storage | Keepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Avoidrepetitivefreeze/thawcycles. |
ExpiryDate | 12monthsafterpurchase |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。