产品编号：KIT-NT-500
市 场 价：¥14940.00
场 地：美国(厂家直采)
联系QQ：1570468124
电话号码：4000-520-616
邮 箱：
info@ebiomall.com
商品介绍
| Description | Neurotrophinsaregrowthfactorsthatregulateneuronaldevelopment,maintenanceandplasticity.Thesehomo-dimericproteinsactivateamultitudeofintracellularsignallingcascadesthroughtheirinteractionwithTrkreceptorsandp75NTR. TheNeurotrophinAntibodyKit(TrialSize)containsacollectionofBiosensispopularsheepantibodiesraisedagainstBDNF(S-015-500),NGF(S-052-500),NT3(S-057-500)andNT4/5(S-059-500).ThekitiscompletedwithonevialofnormalsheepIgG(S-1754-100)foruseasnegativecontrol.ThisfullsizeversionofBiosensisNeurotrophinAntibodyKitcontains500μgsheepIgGofeachantibody. Thiskitpresentsacost-effectivewaytoinvestigateneurotrophinproteinexpressionandfunctionbyimmunologicaltechniquessuchasimmunohistochemistry,ELISA,andinhibitionofBIOLOGicalactivity. |
| Relatedproducts | S-015-500,SheeppolyclonalantibodytorhBDNF S-052-500,SheeppolyclonalantibodytobetaNGF S-057-500,SheeppolyclonalantibodytorhNT3 S-059-500,SheeppolyclonalantibodytorhNT4/5 S-1754-500,NormalsheepIgGfromnon-immunizedanimal |
| BatchNo. | Seeproductlabel. |
| Unitsize | 5vials,eachcontaining500μgsheepIgG |
| Antigen | BDNF:recombinanthumanBDNF NGF:nativemousebetaNGFpurifiedfromsuBMAxillarysalivarygland(95%puritybyPAGE) NT3:recombinanthumanNT3 NT4/5:recombinanthumanNT4 |
| AntibodyType | Polyclonal. |
| Isotype | IgG |
| Accession | P23560BDNF_HUMAN; P01139NGF_MOUSE; P20783NTF3_HUMAN; P34130NTF4_HUMAN; |
| Producedin | Sheep. |
| Purity | ProteinGpurifiedIgG. |
| Applications | Immunohistochemistry:1-10µg/mL.BDNFantibodyworksbestonZamboni"sfixed,frozentissue,andisnotrecommendedforparaffin-embeddedtissue. ELISA:1-10µg/mL. WesternBlotting:1-10µg/mL.WesternblottingisnotrecommendedfortheBDNFantibody. Inhibitionofbiologicalactivityinvitro/invivo:ExpectedED50(invivo)valuesareintherangeof2-10µg/mL.TheNGFantibodycompletelyinhibitsneuronalsurvivalandtheoutgrowthactionsofmurineNGFinchickenDRGinvitro. Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.Thenegativecontrol(normalsheepIgG)shouldbeusedatthesameconcentrationastheneurotrophinantibodies. |
| Specificity | BDNFAntibody:Across-reactivityoflessthan1%againstmouseNGF,recombinanthumanNT3orNT4/5hasbeenshownbyELISA. NGFAntibody:Across-reactivityoflessthan1%againstrecombinanthumanBDNF,NT3andNT4/5byELISAhasbeenshown. NT3Antibody:Across-reactivityoflessthan1%tomouseNGF,recombinanthumanBDNFand5%toNT4/5hasbeenshownbyELISA. NT4/5Antibody:Lessthan1%cross-reactivityagainstNGF,recombinanthumanBDNFand5%toNT3hasbeenshownbydotblot. |
| SpeciesAgainst | Human(BDNF,NT3andNT4/5). Mouse(NGF). |
| Cross-reactivity | Neurotrophinssharealargedegreeofhomologyamonghuman,rodentandothermammalianspecies,thustheseneurotrophinantibodiesareusefulforanumberofspecies,includinghuman,mouseandrat. |
| Form | LyophilizedfromPBS,pH7.4,withoutpreservatives. |
| Appearance | Whitepowder. |
| Reconstitution | Reconstituteeachvialwith500µLsterile-filtered,ultrapurewater,toachieveanantibodyconcentrationof1mg/mL.Centrifugebrieflytoremoveanyinsolublematerial. |
| Storage | Storelyophilised,unopenedvialsat2-8°Corlower.Afterreconstitution,preparealiquotsandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles. |
| ExpiryDate | 12monthsafterpurchase(unopenedvials). |
品牌介绍
Biosensis专注于神经科学领域的抗体和试剂的开发，特别是神经营养因子和神经营养因子受体。 近30年来，Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子，我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症（AD）、帕金森氏症（PD）和肌萎缩侧索硬化（ALS）疾病，以及自噬和代谢应激障碍，包括肥胖、代谢综合征的研究、神经免疫学和炎症。
公司介绍
产品分类
TR-200-BG
PE-1243-50
Antibody Kits
PE-1246-5
TR-100-BG
S-1754-500
Neurotrophic Factors
Diabetes & Obesity
Intracellular Trafficking
PE-1239-5
Neuropeptides & Receptors
B-100-PS
Receptors & Channel Molecules
2 Plate ELISA kits
M-1763-100-FT
TR-200-BGT
PE-1239-2
PE-1242-5
M-1249-100
Neurotrophic Factor Receptors
Cell Cycle Regulators
S-1759-100
PE-1606-100
PE-1762-100
B-200-PS
PE-019-100
PE-1241-5
PE-003-100
1 Plate ELISA kits
BL-003-1000
PE-1246-2
Sensory Nervous System
PE-1253-100
TR-100-FJ
BL-005-500
Neuroendocrine
M-1728-100
DNA Damage & Repair
PE-001-100
PE-1608-1
TR-400-AG
PE-1243-25
Cell Markers
PE-1608-5
TR-100-FJT
Autophagy
PE-1242-2
Other Neuronal
Neurotransmitters & Enzymes
Antioxidant Enzymes
Neuronal Markers
Tag Antibodies
BL-004-500
PE-019-25
PE-1608-10
BL-002-1250
Receptor Body Chimeras
Signalling & Transcription
Matrix & Adhesion Molecules
BL-001-1250
Cancer
PE-019-500
Stem Cells
Junction Proteins
TR-300-AG
Apoptosis
PE-1252-100
Growth Factors
Development
Alzheimer\'s / Parkinson\'s
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总部地址：
江苏省苏州市工业园区星湖街218号 苏州生物医药产业园一期（生物纳米园）A4-216(邮编：215125)
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