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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Neurotrophin Antibody Kit/KIT-NT-500/5 vials, each containing 500 μg sheep IgG
产品编号:KIT-NT-500
市  场 价:¥14940.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$747.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Neurotrophin Antibody Kit/KIT-NT-500/5 vials, each containing 500 μg sheep IgG
商品介绍
DescriptionNeurotrophinsaregrowthfactorsthatregulateneuronaldevelopment,maintenanceandplasticity.Thesehomo-dimericproteinsactivateamultitudeofintracellularsignallingcascadesthroughtheirinteractionwithTrkreceptorsandp75NTR.

TheNeurotrophinAntibodyKit(TrialSize)containsacollectionofBiosensis’popularsheepantibodiesraisedagainstBDNF(S-015-500),NGF(S-052-500),NT3(S-057-500)andNT4/5(S-059-500).ThekitiscompletedwithonevialofnormalsheepIgG(S-1754-100)foruseasnegativecontrol.ThisfullsizeversionofBiosensis’NeurotrophinAntibodyKitcontains500μgsheepIgGofeachantibody.

Thiskitpresentsacost-effectivewaytoinvestigateneurotrophinproteinexpressionandfunctionbyimmunologicaltechniquessuchasimmunohistochemistry,ELISA,andinhibitionofBIOLOGicalactivity.
RelatedproductsS-015-500,SheeppolyclonalantibodytorhBDNF
S-052-500,SheeppolyclonalantibodytobetaNGF
S-057-500,SheeppolyclonalantibodytorhNT3
S-059-500,SheeppolyclonalantibodytorhNT4/5
S-1754-500,NormalsheepIgGfromnon-immunizedanimal
BatchNo.Seeproductlabel.
Unitsize5vials,eachcontaining500μgsheepIgG
AntigenBDNF:recombinanthumanBDNF
NGF:nativemousebetaNGFpurifiedfromsuBMAxillarysalivarygland(95%puritybyPAGE)
NT3:recombinanthumanNT3
NT4/5:recombinanthumanNT4
AntibodyTypePolyclonal.
IsotypeIgG
AccessionP23560BDNF_HUMAN;
P01139NGF_MOUSE;
P20783NTF3_HUMAN;
P34130NTF4_HUMAN;
ProducedinSheep.
PurityProteinGpurifiedIgG.
ApplicationsImmunohistochemistry:1-10µg/mL.BDNFantibodyworksbestonZamboni"sfixed,frozentissue,andisnotrecommendedforparaffin-embeddedtissue.
ELISA:1-10µg/mL.
WesternBlotting:1-10µg/mL.WesternblottingisnotrecommendedfortheBDNFantibody.
Inhibitionofbiologicalactivityinvitro/invivo:ExpectedED50(invivo)valuesareintherangeof2-10µg/mL.TheNGFantibodycompletelyinhibitsneuronalsurvivalandtheoutgrowthactionsofmurineNGFinchickenDRGinvitro.
Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.Thenegativecontrol(normalsheepIgG)shouldbeusedatthesameconcentrationastheneurotrophinantibodies.
SpecificityBDNFAntibody:Across-reactivityoflessthan1%againstmouseNGF,recombinanthumanNT3orNT4/5hasbeenshownbyELISA.
NGFAntibody:Across-reactivityoflessthan1%againstrecombinanthumanBDNF,NT3andNT4/5byELISAhasbeenshown.
NT3Antibody:Across-reactivityoflessthan1%tomouseNGF,recombinanthumanBDNFand5%toNT4/5hasbeenshownbyELISA.
NT4/5Antibody:Lessthan1%cross-reactivityagainstNGF,recombinanthumanBDNFand5%toNT3hasbeenshownbydotblot.
SpeciesAgainstHuman(BDNF,NT3andNT4/5).
Mouse(NGF).
Cross-reactivityNeurotrophinssharealargedegreeofhomologyamonghuman,rodentandothermammalianspecies,thustheseneurotrophinantibodiesareusefulforanumberofspecies,includinghuman,mouseandrat.
FormLyophilizedfromPBS,pH7.4,withoutpreservatives.
AppearanceWhitepowder.
ReconstitutionReconstituteeachvialwith500µLsterile-filtered,ultrapurewater,toachieveanantibodyconcentrationof1mg/mL.Centrifugebrieflytoremoveanyinsolublematerial.
StorageStorelyophilised,unopenedvialsat2-8°Corlower.Afterreconstitution,preparealiquotsandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles.
ExpiryDate12monthsafterpurchase(unopenedvials).
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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