Description | ThisenzymeisathiolproteasethatrecognizesandhydrolyzesapeptidebondattheC-terminalglycineofubiquitin.Theenzymealsobindstofreemonoubiquitinandmaypreventitsdegradationinlysosomes(ref:SWISSPROT). |
BatchNo. | Seeproductlabel |
Unitsize | 100µl |
Antigen | RecombinantfulllengthhumanUbiquitinCTerminalHydrolase1(UCHL1)purifiedfromE.coli. |
AntibodyType | Monoclonal |
Isotype | IgG1 |
Clone | BH7 |
OtherNames | Ubiquitincarboxyl-terminalhydrolaseisozymeL1;UCH-L1;Neuroncytoplasmicprotein9.5;PGP9.5;PGP9.5;UbiquitinthioesteraseL1;UCHL1; |
Accession | P09936UCHL1_HUMAN; |
Producedin | Mouse |
Applications | WesternBlotting(WB),Immunocytochemistry(IC)andImmunohistochemistry(IH).Adilutionof1:20,000isrecommendedforWB.Adilutionof1:500-1:2,000isrecommendedforICandIH.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | ThespecificityofthisantibodyhasbeenconfirmedbyWB.Thisantibodydetects~24kDaUCHL1enzyme.Suitablecontroltissueisratspinalcord,brain,SHSY-5YorHEK293cellextract. |
AntibodyAgainst | UbiquitinCTerminalHydrolase1 |
Cross-reactivity | Hu,Rat,Bov |
BlastURL | Clickhere |
Form | Lyophilisedwith5%trehalose |
Appearance | Whitepowder |
Reconstitution | Reconstituteinsteriledistilledwater.Centrifugetoremoveanyinsolublematerial. |
Storage | Afterreconstitutionoflyophilisedantibody,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles. |
ExpiryDate | 12monthsafterpurchase |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。