| Description | Presenilin-2(PSEN2)isamulti-passmembraneproteinandcomponentofthegamma-secretasecomplex.DefectsinPSEN2areacauseofAlzheimerdiseasetype4(AD4),anautosomaldominantAlzheimerdisease.(Ref:SWISS-Prot). |
| BatchNo. | Seeproductlabel |
| Unitsize | 500µl |
| Antigen | MixtureoftwohumanPresenilin2peptides(319-330and349-360aa).Bothsequencesarehighlyconservedinhuman,mouseandrat. |
| Sequence | GEELEEEEERGVandYDPEMEEDSYDS |
| OtherNames | AD3LP;AD5;E5-1;STM-2;PSEN2;AD4;PS2;PSNL2;STM2;PS-2; |
| Accession | P49810PSN2_HUMAN; |
| Producedin | Chicken |
| Applications | WBandELISA.Suggesteddilutionof1:1,000to1:4,000.Tominimisebackgroundstaining,ahigherconcentrationofdetergent(suchasTween-20)issuggestedinthedilutionandwashingsteps.Biosensisrecommendsthattheoptimalworkingdilutionshouldbedeterminedbytheenduser. |
| Cross-reactivity | Human,Mouse,Rat |
| BlastURL | Clickhere |
| Form | Liquid.PBSwith0.02%SodiumAzide |
| Storage | Shorttermstorageat2-8°Cforoneweek.At-20°Casanundilutedliquidforupto12months. |
| ExpiryDate | 12monthsafterpurchase |
Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。



