Description | Annexin V, also known as Annexin A5, belongs to the annexin family of calcium dependent phospholipid binding proteins. Annexin V has roles in cellular signal transduction, inflammation, growth and differentiation. Annexin V has been shown to have a high affinity for phosphatidylserine (PS) and is therefore a potential probe for the detection of apoptosis. |
Batch No. | See product label |
Unit size | 100 µg |
Antigen | A synthetic peptide corresponding to a region (88-102 aa) from human Annexin V. |
Other Names | Annexin A5; Annexin 5; Lipocortin V; Endonexin II; Calphobindin I; PAP-I; PP4; VAC-alpha; Anchorin CII; CBP-I; ANX5; ENX2; |
Accession | P08758 ANXA5_HUMAN; |
Produced in | Rabbit |
Purity | Affinity purified on antigen column |
Applications | Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5 µg/ml is recommended for WB. Human Annexin V has a predicted length of 320 residues and a MW of 36 kDa. A concentration of 0.5-1 µg/ml is recommended to detect Annexin V in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user. |
Specificity | The specificity of this antibody has been confirmed by WB and IHC against the antigen. |
Cross-reactivity | Human; rat; predicted to react with mouse due to sequence homology; |
Blast URL | Click here |
Form | Lyophilised with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal,0.05mg NaN3 |
Reconstitution | Reconstitute in 100 µl of sterile distilled water to achieve an antibody concentration of 1 mg/ml. Centrifuge to remove any insoluble material. |
Storage | After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles |
Expiry Date | 12 months after purchase |
Specific References | Wei X et al. (2016) "Fatty acid synthesis configures the plasma membrane for inflammation in diabetes." Nature. [Epub ahead of print]. Application: WB. Species: Mouse. |
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