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主营:抗体类、生化类试剂、ELISA试剂盒、组织染色细胞可视化试剂、针对神经科学和细胞疾病研究产品和纯化蛋白等
℡ 4000-520-616
℡ 4000-520-616
Biosensis/Human Stem Cell Factor protein expressed in mammalian cells/PE-1242-2/2 µg
产品编号:PE-1242-2
市  场 价:¥2540.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$127.00
品      牌: Biosensis
公      司:Biosensis
公司分类:
Biosensis/Human Stem Cell Factor protein expressed in mammalian cells/PE-1242-2/2 µg
商品介绍
DescriptionStemCellFactor(SCF)isahematopoieticgrowthfactorthatstimulatestheproliferationofmastcells. SCFalsomediatescell-celladhesionandactssynergisticallywithothercytokines.TheactionsofSCFareexertedbybindingtotheSCFReceptor(PE-1243-50)whichresultsinreceptordimerization.SCFisatypeImembraneglycoproteinwith5potentialN-linkedglycosylationsites.SolubleSCFisproducedbyproteolyticcleavageoftheextracellulardomain.
BatchNo.Seeproductlabel
Unitsize2µg
OtherNamesKitligand;C-kitligand;Stemcellfactor;SCF;Mastcellgrowthfactor;MGF;KITLG;MGF;SCF;
AccessionP21583SCF_HUMAN;
ProducedinHuman-ADNAsequenceencodingthesignalpeptideandthematureStemCellFactor(SCF)proteinofhumanSCFwasexpressedinmodifiedhuman293cells.
MolecularWeightSCFmigratesasabroadbandbetween20and42kDainSDS-PAGEduetopost-translationalmodifications.UnmodifiedSCFhasapredictedmolecularmassof21.0kDa.SCFseparatesintoanumberofisoformswithapIbetween3.0and7.0in2DPAGEduetopost-translationalmodifications.ThiscompareswiththeunmodifiedSCFwithapredictedpIof5.76.
Purity>95%,asdeterminedbySDS-PAGEandvisualizedbysilverstain
Biol.activityTheED50ofSCFistypically10-20ng/mlasmeasuredinacellproliferationassayusingthehumangrowthfactor-dependentM-07ecellline.
FormPurifiedSCFconsistsof0-50%carbohydratebyweight.
ReconstitutionItisrecommendedthat0.5mlofsterilephosphate-bufferedsalinebeaddedtothevial.
StorageLyophilizedproductsshouldbestoredat2-8°C.Followingreconstitution,short-termstorageat4°Cisrecommendedandlonger-termstorageofaliquotsat-18to-20°C.Repeatedfreezethawingisnotrecommended.
品牌介绍

Biosensis专注于神经科学领域的抗体和试剂的开发,特别是神经营养因子和神经营养因子受体。 近30年来,Biosensis一直是该领域的全球领航者和OEM供应商。除神经营养因子,我们的神经科学产品组合还被广泛用于神经退行性疾病、神经发育和神经代谢的研究。重点研究领域包括阿尔茨海默氏症(AD)、帕金森氏症(PD)和肌萎缩侧索硬化(ALS)疾病,以及自噬和代谢应激障碍,包括肥胖、代谢综合征的研究、神经免疫学和炎症。

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